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生物搜索计算:生物信息学搜索结果的整合与全局排名

Bio-Search Computing: integration and global ranking of bioinformatics search results.

作者信息

Masseroli Marco, Ghisalberti Giorgio, Ceri Stefano

机构信息

Dipartimento di Elettronica e Informazione, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, Italy.

出版信息

J Integr Bioinform. 2011 Sep 6;8(2):166. doi: 10.2390/biecoll-jib-2011-166.

Abstract

In the Life Sciences, numerous questions can be addressed only by comprehensively searching different types of data that are inherently ordered, or are associated with ranked confidence values. We previously proposed Search Computing to support the integration of the results of search engines with other data and computational resources. This paper presents how well known bioinformatics resources can be described as search services in the search computing framework and integrated analyses over such services can be carried out. An initial set of bioinformatics services has been described and registered in the search computing framework and a bioinformatics search computing (Bio-SeCo) application using these services has been created. This current prototype application, the available services that it uses, the queries that are supported, the kind of interaction that is therefore made available to the users, and the future scenarios are here described and discussed.

摘要

在生命科学领域,许多问题只有通过全面搜索本质上有序或与排序后的置信度值相关联的不同类型数据才能得到解决。我们之前提出了搜索计算,以支持将搜索引擎的结果与其他数据和计算资源进行整合。本文介绍了如何将知名的生物信息学资源描述为搜索计算框架中的搜索服务,以及如何对这些服务进行综合分析。已经在搜索计算框架中描述并注册了一组初始的生物信息学服务,并创建了一个使用这些服务的生物信息学搜索计算(Bio-SeCo)应用程序。这里描述并讨论了当前的原型应用程序、它所使用的可用服务、支持的查询、为用户提供的交互类型以及未来的场景。

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