Majeed Raphael W, Röhrig Rainer
Department of anesthesia and intensive care medicine Justus-Liebig University Giessen (Germany).
Stud Health Technol Inform. 2011;169:170-4.
Identifying eligible patients is one of the most critical parts of any clinical trial. The process of recruiting patients for the third phase of any clinical trial is usually done manually, informing relevant physicians or putting notes on bulletin boards. While most necessary information is already available in electronic hospital information systems, required data still has to be looked up individually. Most university hospitals make use of a dedicated communication server to distribute information from independent information systems, e.g. laboratory information systems, electronic health records, surgery planning systems. Thus, a theoretical model is developed to formally describe inclusion and exclusion criteria for each clinical trial using a fuzzy ternary logic expression. These expressions will then be used to process HL7 messages from a communication server in order to identify eligible patients.
识别符合条件的患者是任何临床试验中最关键的环节之一。任何临床试验第三阶段的患者招募过程通常都是手动完成的，即通知相关医生或在公告板上张贴通知。虽然大多数必要信息已存在于电子医院信息系统中，但所需数据仍需逐个查找。大多数大学医院利用专用通信服务器来分发来自独立信息系统（如实验室信息系统、电子健康记录、手术规划系统）的信息。因此，开发了一个理论模型，使用模糊三元逻辑表达式来正式描述每个临床试验的纳入和排除标准。然后，这些表达式将用于处理来自通信服务器的HL7消息，以识别符合条件的患者。
