Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD 21287-0842, USA.
Fetal Diagn Ther. 2011;30(4):314-6. doi: 10.1159/000330859. Epub 2011 Sep 2.
Glioneuronal heterotopias are rare malformations composed of differentiated derivates of neuroectodermal tissue that include disorganized neuronal and glial cells. They are typically located extracranially. The nasal cavity represents the most common location. Glioneuronal heterotopias have also been reported in the orbit, pharynx, middle ear, neck and thorax. Rarely, glioneuronal heterotopias may be located intracranially. We are aware of only 15 patients reported with intracranial extra-axial glioneuronal heterotopia (IEGH). We present the prenatal ultrasound and MRI as well as the matching postnatal CT, conventional MRI and diffusion tensor imaging findings of a newborn with an infratentorial IEGH accompanied with craniofacial anomalies.
胶质神经元异位是一种罕见的畸形，由神经外胚层组织的分化衍生物组成，包括结构紊乱的神经元和神经胶质细胞。它们通常位于颅外。鼻腔是最常见的部位。胶质神经元异位也有报道发生在眼眶、咽、中耳、颈部和胸部。罕见情况下，胶质神经元异位也可能位于颅内。我们仅了解到 15 例颅内轴外胶质神经元异位（IEGH）的患者。我们提出了一例伴颅面畸形的幕下 IEGH 新生儿的产前超声、MRI 以及与之匹配的产后 CT、常规 MRI 和弥散张量成像的发现。
