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英国肾脏注册中心第 13 份年度报告(2010 年 12 月):第 8 章:2009 年英国成年血液透析患者的透析充分性:全国和中心特异性分析。

UK Renal Registry 13th Annual Report (December 2010): Chapter 8: adequacy of haemodialysis in UK adult patients in 2009: national and centre-specific analyses.

机构信息

UK Renal Registry, Southmead Hospital, Bristol, UK.

出版信息

Nephron Clin Pract. 2011;119 Suppl 2:c141-7. doi: 10.1159/000331758. Epub 2011 Aug 26.

Abstract

BACKGROUND

Outcome in patients treated with haemodialysis (HD) is influenced by the delivered dose of dialysis. The UK Renal Association (RA) publishes Clinical Practice Guidelines which include recommendations for dialysis dose. The urea reduction ratio (URR) is a widely used measure of dialysis dose.

AIM

To determine the extent to which patients received the recommended dose of HD in the UK.

METHODS

All seventy-two UK renal centres submitted data to the UK Renal Registry (UKRR). Two groups of patients were included in the analyses: the prevalent patient population on 31st December 2009 and the incident patient population for 2009. Centres returning data on <50% of their patient population were excluded from centre-specific comparisons.

RESULTS

Data regarding URR were available from 63 renal centres in the UK. Fifty-one centres provided URR data on more than 90% of prevalent patients. The proportion of patients in the UK who met the UK Clinical Practice Guideline for URR (>65%) increased from 56% in 1998 to 85.5% in 2009. There was considerable variation between centres, with 19 centres attaining the RA clinical practice guideline in >90% of patients and 5 centres attaining the guideline in <70% of patients. The delivered HD dose (URR) was lower in patients who had just commenced dialysis treatment compared to patients who had survived longer on HD.

CONCLUSIONS

The delivered dose of HD for patients with established renal failure has increased over the last decade. Whilst the majority of UK patients achieved the target URR there was considerable variation between centres in the percentage of patients achieving the guideline.

摘要

背景

接受血液透析 (HD) 治疗的患者的预后受透析剂量的影响。英国肾脏协会 (RA) 发布了临床实践指南,其中包括透析剂量的建议。尿素清除率 (URR) 是广泛用于衡量透析剂量的指标。

目的

确定英国患者接受推荐剂量 HD 的程度。

方法

英国所有 72 个肾脏中心向英国肾脏登记处 (UKRR) 提交数据。分析中包括两组患者:2009 年 12 月 31 日的现患患者人群和 2009 年的新发病例患者人群。数据中心返回的患者人数少于其患者总数的 50%,则不参与特定中心的比较。

结果

英国 63 个肾脏中心提供了 URR 数据。51 个中心提供了超过 90%的现患患者的 URR 数据。符合英国临床实践指南 URR (>65%)的患者比例从 1998 年的 56%增加到 2009 年的 85.5%。各中心之间存在较大差异,19 个中心在超过 90%的患者中达到 RA 临床实践指南,而 5 个中心在不到 70%的患者中达到指南。与已经接受 HD 治疗时间较长的患者相比,刚开始透析治疗的患者接受的 HD 剂量 (URR)较低。

结论

过去十年中,接受终末期肾衰竭治疗的患者接受的 HD 剂量有所增加。尽管大多数英国患者达到了目标 URR,但各中心之间达到指南的患者比例存在较大差异。

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