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[一名12岁加蓬男孩的尤因肉瘤]

[Ewing sarcoma in a 12-year-old Gabonese boy].

作者信息

Mouba John Florent, Mimbila-Mayi Mylène, Oyane-Minko Marthe, Minko Julienne, Megnier-Mbo Murielle, Ondo Alain

机构信息

Département de pédiatrie, Hôpital pédiatrique d'Owendo, BP 1208 Libreville, Gabon.

出版信息

Sante. 2011 Apr-Jun;21(2):93-5. doi: 10.1684/san.2011.0248.

Abstract

Ewing sarcoma is a primary malignant bone tumor rarely observed in black populations. We report a case of Ewing sarcoma in a 12-year-old boy, manifested by pain in the lower limbs and pelvis, limping while walking, with functional disability and visual disorders developing over a 2-year period, from 2005 through 2007. The child was transferred for care to South Africa where a biopsy bone was taken and analyzed. The histological slices showed clusters of small round cells, sometimes with indistinct or eosinophilic cytoplasm, oval vesicular nuclei, and fine chromatin. These images were compatible with neoplastic proliferation of small round cells of the Ewing tumor type. We use this case to review the literature and discuss the circumstances of onset and methods of diagnosis.

摘要

尤因肉瘤是一种在黑人人群中罕见的原发性恶性骨肿瘤。我们报告一例12岁男孩的尤因肉瘤病例,其表现为下肢和骨盆疼痛、行走跛行,在2005年至2007年的两年间出现功能障碍和视力障碍。该患儿被转诊至南非接受治疗,在那里进行了骨活检并进行分析。组织学切片显示小圆形细胞簇,有时细胞质不清晰或呈嗜酸性,核呈椭圆形泡状,染色质细腻。这些图像与尤因肿瘤类型的小圆形细胞的肿瘤性增殖相符。我们通过这个病例回顾文献并讨论发病情况和诊断方法。

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