Ghim Jeong-Wook, Baeg Eun Ha, Kim Yun Bok, Jung Min Whan
Neuroscience Laboratory, Institute for Medical Sciences, Ajou University School of Medicine, Suwon, Korea.
Neuroreport. 2011 Nov 16;22(16):824-9. doi: 10.1097/WNR.0b013e32834b93bc.
We have shown previously that stimulus-induced modulation of noise correlation in rat somatosensory cortex conveys additional information about the delivery of tactile stimulation. Here we investigated whether noise correlation is also modulated by an external sensory stimulus in rat prefrontal cortex and, if so, whether such modulation conveys additional information on stimulus delivery. Noise correlation was significantly reduced after the onset of a conditional stimulus (auditory tone) that signaled an electric foot shock in the prefrontal cortex. However, noise correlation contributed little to the transmission of information on stimulus delivery. These results indicate that a meaningful sensory stimulus reduces noise correlation in rat prefrontal cortex, but such modulation does not play a significant role in conveying information on stimulus delivery.
我们之前已经表明，刺激诱导的大鼠体感皮层噪声相关性调制传达了有关触觉刺激传递的额外信息。在这里，我们研究了噪声相关性是否也受到大鼠前额叶皮层外部感觉刺激的调制，如果是，这种调制是否传达了有关刺激传递的额外信息。在额叶前皮质发出电足电击信号的条件刺激（听觉音调）开始后，噪声相关性显著降低。然而，噪声相关性对刺激传递信息的传输贡献很小。这些结果表明，有意义的感觉刺激会降低大鼠前额叶皮层的噪声相关性，但这种调制在传达刺激传递信息方面并不起重要作用。
