Jayasree K, Divya Kn
Department of Pathology, Medical College (VIMS), Bellary, Karnataka, India.
J Cytol. 2011 Jul;28(3):117-20. doi: 10.4103/0970-9371.83469.
Intracranial meningiomas are not often aspirated unless they erode the skull and present as swelling in the head and neck region. We describe the cytologic findings of fine needle aspiration cytology in a clear cell variant of intracranial meningioma presenting with swelling in the left parietal region of the scalp in a 45-year-old woman. The diagnosis was confirmed by histopathology. Clear cell meningioma is characterized by patternless sheets of clear polygonal cells. Clear cell meningioma is a rare distinctive cytological subtype of meningioma with high recurrence rate and increased mortality, which necessitate frequent follow-up after surgical excision. The recognition of clear cell meningiomas is important here and should be distinguished from other clear cell lesions of the scalp. If clear cell epithelial neoplasm is encountered on fine needle aspiration, it is reasonably possible to provide at least a differential diagnosis of meningioma based upon the focal whorls, sparce vascularity on low magnification, along with the presence of pseudoinclusion and inconspicuous nucleoli at high magnification.
除非颅内脑膜瘤侵蚀颅骨并在头颈部区域出现肿胀，否则通常不会进行抽吸。我们描述了一名45岁女性，其颅内脑膜瘤透明细胞变异型在头皮左顶叶区域出现肿胀，细针穿刺细胞学检查的细胞学结果。诊断通过组织病理学得以证实。透明细胞脑膜瘤的特征是无规律排列的透明多边形细胞片。透明细胞脑膜瘤是一种罕见的、独特的脑膜瘤细胞学亚型，复发率高且死亡率增加，手术切除后需要频繁随访。在此，识别透明细胞脑膜瘤很重要，应将其与头皮的其他透明细胞病变区分开来。如果在细针穿刺时遇到透明细胞上皮性肿瘤，基于低倍镜下的局灶性漩涡、稀疏血管，以及高倍镜下的假包涵体和不明显核仁，合理地至少可以提供脑膜瘤的鉴别诊断。
