环丙沙星和左氧氟沙星之间对于速发型超敏反应的交叉敏感性。
Cross sensitivity between ciprofloxacin and levofloxacin for an immediate hypersensitivity reaction.
作者信息
Anovadiya Ashish P, Barvaliya Manish J, Patel Tejas K, Tripathi C B
机构信息
Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat, India.
出版信息
J Pharmacol Pharmacother. 2011 Jul;2(3):187-8. doi: 10.4103/0976-500X.83285.
Abstract
Seven years old male child (24 kg weight) diagnosed as a case of sub acute appendicitis treated with ciprofloxacin, immediately developed multiple erythmatous papules. Reaction subsided after withholding ciprofloxacin and treatment with dexamethasone and chlorpheneramine maleate. It was developed again when treated with levofloxacin and subsided after withdrawal. IgE binding at 7(th) position of core structure of fluoroquinolones likely to be the mechanism. As all the fluoroquinolones have similar core structure, hypersensitivity to one may have cross sensitivity to other fluoroquinolones. It is advisable to avoid other fluoroquinolones and switch over to other group of antibiotics when hypersensitivity to one occurs.
摘要
一名7岁男童（体重24千克）被诊断为亚急性阑尾炎，接受环丙沙星治疗后，立即出现多处红斑丘疹。停用环丙沙星并用地塞米松和马来酸氯苯那敏治疗后，反应消退。使用左氧氟沙星治疗时再次出现，停药后消退。氟喹诺酮类药物核心结构第7位的IgE结合可能是其机制。由于所有氟喹诺酮类药物都有相似的核心结构，对一种药物过敏可能对其他氟喹诺酮类药物有交叉过敏反应。当对一种药物过敏时，建议避免使用其他氟喹诺酮类药物，改用其他抗生素组。
相似文献
1
Cross sensitivity between ciprofloxacin and levofloxacin for an immediate hypersensitivity reaction.环丙沙星和左氧氟沙星之间对于速发型超敏反应的交叉敏感性。
J Pharmacol Pharmacother. 2011 Jul;2(3):187-8. doi: 10.4103/0976-500X.83285.
2
Immediate Hypersensitivity to Fluoroquinolones:
A Cohort Assessing Cross-Reactivity.对氟喹诺酮类药物的速发型超敏反应：一项评估交叉反应性的队列研究
Open Forum Infect Dis. 2022 Mar 2;9(4):ofac106. doi: 10.1093/ofid/ofac106. eCollection 2022 Apr.
3
Ciprofloxacin-Induced Anaphylactic Reaction Followed by Negative Provocation Test in Response to Levofloxacin: A Case Report.环丙沙星致过敏反应，左氧氟沙星激发试验阴性：1 例报告。
Medicina (Kaunas). 2023 Oct 7;59(10):1784. doi: 10.3390/medicina59101784.
4
Relationships among ciprofloxacin, gatifloxacin, levofloxacin, and norfloxacin MICs for fluoroquinolone-resistant Escherichia coli clinical isolates.环丙沙星、加替沙星、左氧氟沙星和诺氟沙星对耐氟喹诺酮类大肠杆菌临床分离株的最低抑菌浓度（MIC）之间的关系。
Antimicrob Agents Chemother. 2009 Jan;53(1):229-34. doi: 10.1128/AAC.00722-08. Epub 2008 Oct 6.
5
Pharmacokinetics of sunitinib in combination with fluoroquinolones in rabbit model.舒尼替尼与氟喹诺酮类药物在兔模型中的药代动力学。
Pharmacol Rep. 2013;65(5):1383-90. doi: 10.1016/s1734-1140(13)71497-x.
6
Fluoroquinolone resistance of Pseudomonas aeruginosa isolates causing nosocomial infection is correlated with levofloxacin but not ciprofloxacin use.铜绿假单胞菌引起医院感染的氟喹诺酮类耐药与左氧氟沙星而非环丙沙星的使用相关。
Int J Antimicrob Agents. 2010 Mar;35(3):261-4. doi: 10.1016/j.ijantimicag.2009.11.007. Epub 2009 Dec 31.
7
Immediate hypersensitivity to moxifloxacin with tolerance to ciprofloxacin: report of three cases and review of the literature.对莫西沙星即刻过敏而对环丙沙星耐受：三例报告及文献复习。
Ann Pharmacother. 2010 Apr;44(4):740-5. doi: 10.1345/aph.1M579. Epub 2010 Mar 16.
8
Fluoroquinolone resistance in Bacteroides fragilis following sparfloxacin exposure.司帕沙星暴露后脆弱拟杆菌对氟喹诺酮类药物的耐药性
Antimicrob Agents Chemother. 1999 Sep;43(9):2251-5. doi: 10.1128/AAC.43.9.2251.
9
Binding characteristics of fluoroquinolones to synthetic levodopa melanin.氟喹诺酮类药物与合成左旋多巴黑色素的结合特性
J Pharm Pharmacol. 2003 Aug;55(8):1127-33. doi: 10.1211/002235703322277168.
10
Comparative in vitro activity of three fluoroquinolones against clinical isolates by E test.通过E试验比较三种氟喹诺酮类药物对临床分离株的体外活性。
Chemotherapy. 2003 Jul;49(4):184-8. doi: 10.1159/000071142.
引用本文的文献
1
Ciprofloxacin-Induced Anaphylactic Reaction Followed by Negative Provocation Test in Response to Levofloxacin: A Case Report.环丙沙星致过敏反应，左氧氟沙星激发试验阴性：1 例报告。
Medicina (Kaunas). 2023 Oct 7;59(10):1784. doi: 10.3390/medicina59101784.
2
Immediate Hypersensitivity to Fluoroquinolones:
A Cohort Assessing Cross-Reactivity.对氟喹诺酮类药物的速发型超敏反应：一项评估交叉反应性的队列研究
Open Forum Infect Dis. 2022 Mar 2;9(4):ofac106. doi: 10.1093/ofid/ofac106. eCollection 2022 Apr.
3
Trends in the Design of Intensity-Based Optical Fiber Biosensors (2010-2020).基于强度的光纤生物传感器设计的发展趋势（2010-2020 年）。
Biosensors (Basel). 2021 Jun 15;11(6):197. doi: 10.3390/bios11060197.
4
Quinolone Allergy.喹诺酮类过敏
Pharmacy (Basel). 2019 Jul 19;7(3):97. doi: 10.3390/pharmacy7030097.
5
Immediate type hypersensitivity and late phase reaction occurred consecutively in a patient receiving ethambutol and levofloxacin.一名接受乙胺丁醇和左氧氟沙星治疗的患者连续出现速发型超敏反应和迟发相反应。
Allergy Asthma Clin Immunol. 2018 Apr 3;14:13. doi: 10.1186/s13223-018-0237-x. eCollection 2018.
6
Food entries in a large allergy data repository.大型过敏数据存储库中的食物条目。
J Am Med Inform Assoc. 2016 Apr;23(e1):e79-87. doi: 10.1093/jamia/ocv128. Epub 2015 Sep 17.
7
Cutaneous adverse drug reactions in Indian population: A systematic review.印度人群中的皮肤药物不良反应：一项系统综述。
Indian Dermatol Online J. 2014 Dec;5(Suppl 2):S76-86. doi: 10.4103/2229-5178.146165.
8
Safe medication use based on knowledge of information about contraindications concerning cross allergy and comprehensive clinical intervention.基于对交叉过敏和综合临床干预相关禁忌信息的了解，安全用药。
Ther Clin Risk Manag. 2013;9:65-72. doi: 10.2147/TCRM.S42013. Epub 2013 Feb 26.
本文引用的文献
1
In vivo diagnostic tests in adverse reactions to quinolones.
J Investig Allergol Clin Immunol. 2007;17(6):393-8.
2
Sulfonamide allergy and cross-reactivity.磺胺类药物过敏与交叉反应。
Curr Allergy Asthma Rep. 2007 Apr;7(1):41-8. doi: 10.1007/s11882-007-0029-8.
3
Cross-reactivity of beta-lactam antibiotics.β-内酰胺类抗生素的交叉反应性。
Proc (Bayl Univ Med Cent). 2001 Jan;14(1):106-7. doi: 10.1080/08998280.2001.11927741.
4
Immediate hypersensitivity to quinolones: moxifloxacin cross-reactivity.对喹诺酮类药物的速发型超敏反应：莫西沙星交叉反应性。
J Investig Allergol Clin Immunol. 2005;15(2):146-9.
5
Comparison of side effects of levofloxacin versus other fluoroquinolones.左氧氟沙星与其他氟喹诺酮类药物副作用的比较。
Chemotherapy. 2001;47 Suppl 3:9-14; discussion 44-8. doi: 10.1159/000057839.
6
Focusing on the preventability of adverse drug reactions.关注药物不良反应的可预防性。
Hosp Pharm. 1992 Jun;27(6):538.
7
Fixed eruption caused by ciprofloxacin with cross-sensitivity to norfloxacin.由环丙沙星引起的固定性药疹，对诺氟沙星有交叉敏感性。
Allergy. 1993 May;48(4):296-7. doi: 10.1111/j.1398-9995.1993.tb00733.x.
8
A method for estimating the probability of adverse drug reactions.一种估算药物不良反应概率的方法。
Clin Pharmacol Ther. 1981 Aug;30(2):239-45. doi: 10.1038/clpt.1981.154.
9
Structure-activity relationships of the fluoroquinolones.氟喹诺酮类药物的构效关系。
Antimicrob Agents Chemother. 1989 Feb;33(2):131-5. doi: 10.1128/AAC.33.2.131.
10
Preventability and severity assessment in reporting adverse drug reactions.药品不良反应报告中的可预防性和严重程度评估
Am J Hosp Pharm. 1992 Sep;49(9):2229-32.
Zotero 插件