Brar K S, Garg M K, Suryanarayana K M
Department of Endocrinology, Army Hospital (Research and Referral), Delhi Cantt, New Delhi, India.
Indian J Endocrinol Metab. 2011 Jul;15(3):170-4. doi: 10.4103/2230-8210.83400.
Hypopituitarism, a disease of varied etiologies, is a serious endocrine illness that requires early recognition and prompt treatment to avoid its severe deleterious effects. In adults it is often missed due to non-specific symptoms of growth hormone deficiency and hypogonadism or mild deficiencies of other pituitary hormones. In some it may present with acute onset of symptoms suggestive of acute adrenal (corticotropin) insufficiency or symptoms due to mass lesion in/or around pituitary. High index of suspicion is required to seek hypopituitarism in patients with non-specific symptoms such as fatigue and malaise. Treatment of isolated hormone deficiency, partial or panhypopituitarism, has gratifying results although they require lifelong treatment and follow-up.
垂体功能减退症病因多样，是一种严重的内分泌疾病，需要早期识别并及时治疗，以避免其产生严重的有害影响。在成年人中，由于生长激素缺乏和性腺功能减退的非特异性症状或其他垂体激素的轻度缺乏，该病常常被漏诊。在一些患者中，可能会出现提示急性肾上腺（促肾上腺皮质激素）功能不全的急性症状，或因垂体内部或周围的占位性病变而出现症状。对于出现疲劳和不适等非特异性症状的患者，需要高度怀疑垂体功能减退症。尽管孤立性激素缺乏、部分或全垂体功能减退症需要终身治疗和随访，但治疗效果令人满意。
