Faculty of Physics, A. Mickiewicz University, Umultowska 85, PL-61-614 Poznań, Poland.
Phys Chem Chem Phys. 2011 Oct 21;13(39):17722-8. doi: 10.1039/c1cp21819k. Epub 2011 Sep 6.
Recent measurements of lysozyme hydration water density under non-denaturing pressure show that it is higher than that of bulk water in the same conditions. High protein hydration layer density has earlier been observed at ambient conditions and ascribed to electrostriction. We calculate the pressure-induced protein mean surface charge density increment Δσ. Within the hydration layer, the higher fields due to Δσ lead to an additional water compression via electrostriction. The increment Δσ is considered as due to a mechanoelectric effect in protein molecules. The mean value of the effective mechanoelectric coefficient d is calculated and compared with piezoelectric coefficients of amino acids and their compounds.
最近在非变性压力下对溶菌酶水合层密度的测量表明，其在相同条件下高于体相水。在环境条件下，先前已经观察到高蛋白质水合层密度，并归因于电致伸缩。我们计算了压力诱导的蛋白质平均表面电荷密度增量 Δσ。在水合层内，由于 Δσ 引起的较高电场通过电致伸缩导致水的额外压缩。增量 Δσ 被认为是由于蛋白质分子中的机电效应引起的。计算了有效机电系数 d 的平均值，并与氨基酸及其化合物的压电系数进行了比较。
