Department of Rheumatology, China-Japan Friendship Hospital, Yinghua East Road, Chaoyang District, Beijing 100029, China.
Rheumatol Int. 2012 Oct;32(10):2993-7. doi: 10.1007/s00296-011-2103-8. Epub 2011 Sep 7.
Systemic lupus erythematosus predominantly affects young women during childbearing age. It is rare after the age of 90, and there is no report of very late onset in persons over 90 in China. Here, we reported a case of a female patient, the onset age of whom was 90, analyzing her clinical features and treatments. And when conducting a pooled analysis of late-onset cases in the literature, we found that the organ damages and severity of lupus disease of old-onset SLE were not benign, and considering their ages, comorbidities and high rate of mortalities, appropriate interventions and close follow-up for this age group are needed.
系统性红斑狼疮主要影响生育年龄的年轻女性。90 岁以后很少见，在中国，90 岁以上的患者没有很晚发病的报道。在这里，我们报告了一例女性患者，其发病年龄为 90 岁，分析了她的临床特征和治疗方法。在对文献中迟发性病例进行汇总分析时，我们发现老年发病的 SLE 的器官损害和狼疮疾病的严重程度并非良性，考虑到他们的年龄、合并症和高死亡率，需要对这一年龄组进行适当的干预和密切随访。
