Abdel-Hafez S H, Saad H A, Aly M R E
Chemistry Department, Faculty of Science, Taif University, 888, Alhawiya, Taif University, Tai, Kingdom of Saudi Arabia.
Bioorg Khim. 2011 May-Jun;37(3):293-301. doi: 10.1134/s1068162011030034.
Synthesis of selenium-containing amino acid analogues is described. These compounds were prepared in a concise and short synthetic route in good yields by nucleophilic substitution reaction of pyridineselenol and quinolineselenol derivatives with N-phthaloylglycyl chloride followed by hydrazinolysis. The newly synthesized compounds were screened against different strains of bacteria and fungi.
描述了含硒氨基酸类似物的合成。这些化合物通过吡啶硒醇和喹啉硒醇衍生物与N-邻苯二甲酰甘氨酰氯的亲核取代反应，随后进行肼解，以简洁的短合成路线高收率制备。对新合成的化合物针对不同的细菌和真菌菌株进行了筛选。
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