The Institute of Liver Studies, King's College Hospital, London.
Clin Med (Lond). 2011 Jun;11(3):254-8. doi: 10.7861/clinmedicine.11-3-254.
ALF is a multisystem disorder necessitating both predictive and reactive management strategies to support and protect organs from the initial and subsequent insults encountered. Early referral to a specialist liver centre with the option of liver transplantation is recommended. Furthermore, a good understanding of the poor prognostic variables is necessary to determine those most at risk of developing ALF in order to facilitate timely, safe transfer and listing for liver transplantation.
ALF 是一种多系统疾病,需要采取预测性和反应性的管理策略,以支持和保护器官免受最初和随后遇到的损伤。建议早期转至专门的肝脏中心,并可选择进行肝移植。此外,需要很好地了解预后不良的变量,以确定那些最有可能发展为 ALF 的患者,以便及时、安全地转院并进行肝移植。