Institute for Theoretical Physics, Utrecht University, The Netherlands.
Phys Rev Lett. 2011 Aug 5;107(6):068101. doi: 10.1103/PhysRevLett.107.068101. Epub 2011 Aug 1.
Recent experiments of translocation of double-stranded DNA through nanopores [M. Wanunu et al., Nature Nanotech. 5, 160 (2009)] reveal that the DNA capture rate can be significantly influenced by a salt gradient across the pore. We show that osmotic flow combined with electrophoretic effects can quantitatively explain the experimental data on the salt-gradient dependence of the capture rate.
最近通过纳米孔进行双链 DNA 转位的实验[M. Wanunu 等人，《自然纳米技术》5,160（2009）]表明，DNA 捕获率可以通过跨孔的盐梯度显著影响。我们表明，渗透压流与电泳效应相结合可以定量解释关于捕获率与盐梯度依赖性的实验数据。
