Rasina L N, Chupakhin O N, Chibiriak M V
Radiobiologiia. 1990 Mar-Apr;30(2):162-5.
Some thiazole, triazole, thiadiazine, and heterylalkane derivatives increased the lifespan of gamma-irradiated (9-14 Gy) mice up to 6-22 days (as opposed to 4.1 days in the irradiated control). The efficacy of chemical agents within the dose range mentioned above was mainly associated with protecting intestinal epithelium stem cells the number of which was 4-9 times as large as that of nontreated animals. There was a moderate (40-50%) decrease in oxygen consumption under the effect of the most active radioprotectors.
一些噻唑、三唑、噻二嗪和杂烷基衍生物可使经γ射线照射（9 - 14 Gy）的小鼠寿命延长6 - 22天（与之相比，照射对照组小鼠寿命延长4.1天）。上述剂量范围内化学药剂的功效主要与保护肠道上皮干细胞有关，经药剂处理的小鼠肠道上皮干细胞数量是未处理动物的4 - 9倍。在最具活性的辐射防护剂作用下，氧气消耗量有适度（40 - 50%）下降。
