[Mechanisms of the protective action of sulfur-containing radioprotectors on the intestinal epithelium].
作者信息
Vladimirov V G, Grigor'eva E V
出版信息
Radiobiologiia. 1990 May-Jun;30(3):348-52.
PMID:2164697
Abstract
In studying the influence of cystamine and gammaphos on the recovery of mouse jejunum epithelium after irradiation with doses inducing intestinal form of acute radiation sickness, it was shown that the radioprotective agents did not influence D0 value for intestinal epithelium stem cells, but in crypts the number of DNA-synthesizing enterocytes that entered mitosis increased after the preventive administration of the radioprotectors. All this caused the number of cells per villus to increase and intestinal mucosa to recover more readily.
摘要
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