Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland.
Burns. 2012 Mar;38(2):274-82. doi: 10.1016/j.burns.2011.08.009. Epub 2011 Sep 7.
Split-thickness skin autografts are the gold-standard in providing permanent acute wound closure in major burns. Split-thickness dermal grafts harvested from the same donor site may provide an additional autologous option for permanent acute coverage and increase the number of potential autologous donor sites.
We performed 16 dermis grafts (DG) harvested from the skin of the back in 9 consecutive burn patients. A control donor site consisted of an area of adjacent back skin from which a standard split-thickness skin graft was harvested. The mean age was 63 years (range 23-79 years). The mean initial burn size was 24% TBSA (range 2-40% TBSA). The size of the 16 DG recipient wound beds ranged from 20 to 180 cm2, with mean and median sizes of 62 and 45 cm2, respectively.
Dermis graft take was complete in 15/16 cases. All grafts recorded >90% epithelialisation by 4 weeks. There was no significant difference in dermis graft and control donor site healing times (p value 0.05).
Dermis grafts can provide an additional autologous option for permanent coverage in acute major burn wounds without increasing donor site size or morbidity.
全厚皮片移植是治疗大面积烧伤提供永久性急性创面封闭的金标准。取自同一供体部位的全厚真皮移植物可为永久性急性覆盖提供额外的自体选择,并增加潜在的自体供体部位数量。
我们对 9 例连续烧伤患者的背部皮肤进行了 16 例真皮移植(DG)。对照供体部位为取自相邻背部皮肤的标准全厚皮片移植供体部位。平均年龄为 63 岁(范围 23-79 岁)。初始烧伤面积平均为 24%TBSA(范围 2-40%TBSA)。16 例 DG 受区创面床的大小从 20 到 180cm2 不等,平均和中位数大小分别为 62 和 45cm2。
15/16 例 DG 完全存活。所有移植物在 4 周内均>90%上皮化。真皮移植物和对照供体部位的愈合时间无显著差异(p 值 0.05)。
真皮移植物可作为治疗大面积烧伤急性创面永久性覆盖的额外自体选择,而不会增加供体部位的大小或发病率。