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急性胰腺炎诱发的血栓性血小板减少性紫癜。

Thrombotic thrombocytopenic purpura precipitated by acute pancreatitis.

作者信息

Chaudhry Mohammed Suhail, Saweirs Martin W M

机构信息

Department of Haematology, Hammersmith Hospital, London, UK.

出版信息

Transfus Apher Sci. 2011 Oct;45(2):143-7. doi: 10.1016/j.transci.2011.07.009. Epub 2011 Sep 8.

DOI:10.1016/j.transci.2011.07.009
PMID:21903475
Abstract

A 20 year old woman, admitted with acute pancreatitis, subsequently developed microangiopathic haemolytic anaemia, thrombocytopenia and mild neurological compromise. A diagnosis of thrombotic thrombocytopenic purpura (TTP) was made, and she was treated with plasma exchange leading to complete resolution of this condition. TTP is a rare multisystem disorder which may be life threatening if not treated promptly. The increasing recognition of acute pancreatitis as a potential aetiological factor offers new insights into the pathogenesis, diagnosis and treatment of TTP.

摘要

一名20岁女性因急性胰腺炎入院,随后出现微血管病性溶血性贫血、血小板减少和轻度神经功能损害。诊断为血栓性血小板减少性紫癜(TTP),她接受了血浆置换治疗,病情完全缓解。TTP是一种罕见的多系统疾病,如果不及时治疗可能危及生命。急性胰腺炎作为潜在病因的认识不断增加,为TTP的发病机制、诊断和治疗提供了新的见解。

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