Li Feng, Seillier-Moiseiwitsch Françoise
Bioinformation. 2011;6(10):389-90. doi: 10.6026/97320630006389. Epub 2011 Aug 2.
Image analysis of two-dimensional gel electrophoresis is a key step in proteomic workflow for identifying proteins that change under different experimental conditions. Since there are usually large amount of proteins and variations shown in the gel images, the use of software for analysis of 2D gel images is inevitable. We developed open-source software with graphical user interface for differential analysis of 2D gel images. The user-friendly software, RegStatGel, contains fully automated as well as interactive procedures. It was developed and has been tested under Matlab 7.01.
The database is available for free at http://www.mediafire.com/FengLi/2DGelsoftware.
二维凝胶电泳的图像分析是蛋白质组学工作流程中识别在不同实验条件下发生变化的蛋白质的关键步骤。由于凝胶图像中通常显示有大量蛋白质和变异，因此使用软件分析二维凝胶图像是不可避免的。我们开发了具有图形用户界面的开源软件，用于二维凝胶图像的差异分析。这款用户友好型软件RegStatGel包含全自动和交互式程序。它是在Matlab 7.01下开发并经过测试的。
