Jones Guy C, Elaimy Ameer L, Demakas John J, Jiang Hansi, Lamoreaux Wayne T, Fairbanks Robert K, Mackay Alexander R, Cooke Barton S, Lee Christopher M
Department of Radiation Oncology, Gamma Knife of Spokane, 910 West 5th Avenue, Suite 102, Spokane, WA 99204, USA.
Case Rep Med. 2011;2011:258910. doi: 10.1155/2011/258910. Epub 2011 Sep 4.
Treatment options for trigeminal neuralgia (TN) must be customized for the individual patient, and physicians must be aware of the medical, surgical, and radiation treatment modalities to prescribe optimal treatment courses for specific patients. The following case illustrates the potential for gamma knife radiosurgery (GKRS) to be repeated multiple times for the purpose of achieving facial pain control in cases of TN that have been refractory to other medical and surgical options, as well as prior GKRS. The patient described failed to achieve pain control with initial GKRS, as well as medical and surgical treatments, but experienced significant pain relief for a period of time with a second GKRS procedure and later underwent a third procedure. Only a small subset of patients have reportedly undergone more than two GKRS for TN; thus, further research and long-term clinical followup will be valuable in determining its usefulness in specific clinical situations.
三叉神经痛（TN）的治疗方案必须根据个体患者进行定制，医生必须了解医学、外科和放射治疗方式，以便为特定患者开出最佳治疗方案。以下病例说明了伽玛刀放射外科手术（GKRS）有可能多次重复进行，目的是在TN患者中实现面部疼痛控制，这些患者对其他医学和外科选择以及先前的GKRS均无反应。所述患者最初的GKRS以及药物和手术治疗均未能实现疼痛控制，但第二次GKRS手术使其在一段时间内疼痛得到显著缓解，后来又接受了第三次手术。据报道，只有一小部分TN患者接受过两次以上的GKRS治疗；因此，进一步的研究和长期临床随访对于确定其在特定临床情况下的有效性将具有重要价值。
