Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Chem Commun (Camb). 2011 Oct 21;47(39):11047-9. doi: 10.1039/c1cc14024h. Epub 2011 Sep 9.
A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL(-1).
本研究使用金包覆的磁性纳米簇和动态光散射（DLS）方法，开发了一种用于检测甲胎蛋白（AFP）的简便、灵敏的免疫分析方法。利用 DLS 测量了由于 AFP 介导的聚集导致的平均粒径增加，检测限优于 0.01ng/mL。
