Department of Plastic Surgery, St. Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK.
Arch Gynecol Obstet. 2012 Apr;285(4):1153-6. doi: 10.1007/s00404-011-2018-3. Epub 2011 Sep 9.
This case report presents a 52-year-old woman with a submental swelling which arose 3 years after wide local excision and axillary lymphadenectomy for breast carcinoma. Histopathological examination after excision biopsy of this lesion confirmed the presence of invasive breast carcinoma in a submental lymph node. Computed tomography of the head, neck, thorax, abdomen and pelvis demonstrated multiple brain and pulmonary metastases. Further management was palliative and the patient died 5 months later. This is the first description of a breast carcinoma metastasising to the submental region. Metastatic breast carcinoma should be considered in the differential diagnosis of head and neck lymphadenopathy in patients with previously diagnosed breast carcinoma.
本病例报告介绍了一位 52 岁女性，她在因乳腺癌行广泛局部切除和腋窝淋巴结清扫术后 3 年出现颏下肿胀。切除活检后组织病理学检查证实该病变存在颏下淋巴结内浸润性乳腺癌。头颈部、胸部、腹部和骨盆的计算机断层扫描显示多个脑和肺转移灶。进一步的治疗为姑息性，患者 5 个月后死亡。这是首例乳腺癌转移至颏下区域的描述。对于既往诊断为乳腺癌的患者，头颈部淋巴结病的鉴别诊断中应考虑转移性乳腺癌。
