Tabar M-D, Maggi R G, Altet L, Vilafranca M, Francino O, Roura X
Hospital Veterinario San Vicente, Cami del Rodalet 17, San Vicente del Raspeig, Alicante, Spain.
J Small Anim Pract. 2011 Apr;52(4):209-12. doi: 10.1111/j.1748-5827.2011.01046.x.
Generalised pyogranulomatous disease and hyperviscosity syndrome associated with a presumed monoclonal gammopathy was diagnosed in a three-year-old intact female Pomeranian. The Bartonella henselae antibody titer was 1:64 and Bartonella species DNA was amplified from the splenic tissue. Monoclonal gammopathies in dogs are typically associated with plasma cell and lymphoid dyscrasias and other inflammatory or infectious diseases such as ehrlichiosis and leishmaniosis. Based on this case report, infection with Bartonella species should also be added to the differential diagnoses for gammopathy in dogs. To the authors' knowledge, this is the first report of molecular evidence of Bartonella species infection in a sick dog in Spain.
一只三岁未绝育的雌性博美犬被诊断出患有与疑似单克隆丙种球蛋白病相关的全身性脓性肉芽肿病和高黏滞综合征。汉氏巴尔通体抗体滴度为1:64，并且从脾脏组织中扩增出了巴尔通体属DNA。犬类的单克隆丙种球蛋白病通常与浆细胞和淋巴样发育异常以及其他炎症或感染性疾病有关，如埃立克体病和利什曼病。基于本病例报告，巴尔通体属感染也应添加到犬类丙种球蛋白病的鉴别诊断中。据作者所知，这是西班牙一只患病犬中巴尔通体属感染分子证据的首次报告。
