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一名幼儿因蛙粪霉引起的严重皮肤接合菌病。

Severe cutaneous zygomycosis due to Basidiobolus ranarum in a young infant.

作者信息

Mendiratta Vibhu, Karmakar Somenath, Jain Arpita, Jabeen Masarat

机构信息

Department of Dermatology, Lady Hardinge Medical College, Delhi, India.

出版信息

Pediatr Dermatol. 2012 Jan-Feb;29(1):121-3. doi: 10.1111/j.1525-1470.2011.01476.x. Epub 2011 Sep 9.

Abstract

Basidiobolomycosis classically presents as a noninflammatory, nonulcerated, nontender woody indurated mass without much contiguous spread. It is almost always seen in an immunocompetent host younger than 20. We report a case of a 9-month-old baby with a rapidly expanding malignant presentation of basidiobolomycosis with nonhealing ulcers and spread to underlying muscles, mimicking lymphoma. She responded poorly to itraconazole alone but showed dramatic improvement with a combination therapy of itraconazole and potassium iodide. The case also highlights an early acquisition of the infection at 1 month of age.

摘要

担子菌病通常表现为非炎症性、非溃疡性、无压痛的木质硬结肿块,无明显的连续性扩散。几乎总是在20岁以下的免疫功能正常宿主中出现。我们报告一例9个月大婴儿,患有担子菌病的快速进展的恶性表现,伴有不愈合溃疡并蔓延至深层肌肉,类似淋巴瘤。她单独使用伊曲康唑治疗效果不佳,但伊曲康唑和碘化钾联合治疗后有显著改善。该病例还突出了在1个月大时就早期感染了该病。

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