Lee Timmy, Mokrzycki Michele, Moist Louise, Maya Ivan, Vazquez Miguel, Lok Charmaine E
Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Semin Dial. 2011 Sep-Oct;24(5):515-24. doi: 10.1111/j.1525-139X.2011.00969.x. Epub 2011 Sep 9.
Vascular access dysfunction is one of the leading causes of morbidity and mortality among end-stage renal disease patients. Vascular access dysfunction exists in all three types of available accesses: arteriovenous fistulas, arteriovenous grafts, and tunneled catheters. To improve clinical research and outcomes in hemodialysis (HD) access dysfunction, the development of a multidisciplinary network of collaborative investigators with various areas of expertise, and common standards for terminology and classification in all vascular access types, is required. The North American Vascular Access Consortium (NAVAC) is a newly formed multidisciplinary and multicenter network of experts in the area of HD vascular access, who include nephrologists and interventional nephrologists from the United States and Canada with: (1) a primary clinical and research focus in HD vascular access dysfunction, (2) national and internationally recognized experts in vascular access, and (3) a history of productivity measured by peer-reviewed publications and funding among members of this consortium. The consortium's mission is to improve the quality and efficiency in vascular access research, and impact the research in the area of HD vascular access by conducting observational studies and randomized controlled trials. The purpose of the consortium's initial manuscript is to provide working and standard vascular access definitions relating to (1) epidemiology, (2) vascular access function, (3) vascular access patency, and (4) complications in vascular accesses relating to each of the vascular access types.
血管通路功能障碍是终末期肾病患者发病和死亡的主要原因之一。三种可用的血管通路类型,即动静脉内瘘、动静脉移植物和带隧道的导管,均存在血管通路功能障碍。为了改善血液透析(HD)血管通路功能障碍的临床研究及治疗效果,需要建立一个由具有不同专业领域的合作研究者组成的多学科网络,并制定所有血管通路类型的术语和分类通用标准。北美血管通路联盟(NAVAC)是一个新成立的HD血管通路领域的多学科、多中心专家网络,成员包括来自美国和加拿大的肾脏病学家和介入肾脏病学家,他们具备以下特点:(1)主要临床和研究重点为HD血管通路功能障碍;(2)是血管通路领域国内和国际公认的专家;(3)通过同行评审出版物和该联盟成员获得的资金衡量,具有较高的产出历史。该联盟的使命是提高血管通路研究的质量和效率,并通过开展观察性研究和随机对照试验,影响HD血管通路领域的研究。该联盟初始稿件的目的是提供与(1)流行病学、(2)血管通路功能、(3)血管通路通畅性以及(4)与每种血管通路类型相关的血管通路并发症有关的实用和标准血管通路定义。