Tchabi S, Abouki C, Sounouvou I, Yèhouessi L, Doutetien C, Bassabi S K
Clinique ophtalmologique, centre national hospitalier universitaire Hubert-Koutoukou-Maga, 03, BP 1357, Cotonou, Bénin.
J Fr Ophtalmol. 2011 Nov;34(9):624-8. doi: 10.1016/j.jfo.2011.07.009. Epub 2011 Sep 8.
To survey patient understanding of primary open-angle glaucoma (POAG) and difficulties associated with medical treatment of POAG patients, to determine patient compliance rates with medical therapy, to study factors influencing compliance rates, and to formulate suggestions to improve patient compliance.
Our descriptive prospective study was carried out at the ophthalmology clinic of the Hubert K. Maga national university medical center and in the "La Lumière" ophthalmology clinic in Cotonou, from January 5 through April 25, 2009. The study included all glaucoma patients under medical treatment for at least 1 year with no surgical POAG intervention, seen in consultation during the study period, i.e. 120 patients. The following parameters were studied: whether the patient took or forgot to take his or her medication within the week preceding the survey, the patient's statement of whether or not voluntary interruption of antiglaucoma treatment occurred for more than 1 day, and the regularity of follow-up appointments with the doctor over the preceding 2 years.
The median age of the patients was 56.5 ± 11.9years. A percentage of 90.8 of patients understood the chronic nature of POAG. A percentage of 91.7 knew that, in the absence of treatment, POAG can result in irreversible blindness. A percentage of 90 knew that medical treatment is intended to be lifelong. A percentage of 84.2 knew that the dosing schedule must be adhered to. The rate of total compliance was 53.3%. Only regularity of follow-up visits and adherence to dosing schedules were found as significant factors (P<0.05).
Compliance is a dynamic variable which ophthalmologists need to evaluate throughout the follow-up of POAG patients, in order to reduce the prevalence of glaucoma blindness in Bénin.
调查患者对原发性开角型青光眼（POAG）的了解情况以及POAG患者药物治疗相关的困难，确定患者药物治疗的依从率，研究影响依从率的因素，并制定提高患者依从性的建议。
我们的描述性前瞻性研究于2009年1月5日至4月25日在休伯特·K·马加国立大学医学中心眼科诊所和科托努的“拉卢米埃尔”眼科诊所进行。该研究纳入了所有在研究期间前来就诊、接受药物治疗至少1年且未接受过POAG手术干预的青光眼患者，共120例。研究了以下参数：在调查前一周内患者是否服用或忘记服用药物、患者关于抗青光眼治疗是否自愿中断超过1天的陈述以及过去2年与医生随访预约的规律性。
患者的中位年龄为56.5±11.9岁。90.8%的患者了解POAG的慢性性质。91.7%的患者知道在未治疗的情况下，POAG可导致不可逆性失明。90%的患者知道药物治疗是终身的。84.2%的患者知道必须遵守给药时间表。总依从率为53.3%。仅发现随访的规律性和遵守给药时间表是显著因素（P<0.05）。
依从性是一个动态变量，眼科医生在POAG患者的整个随访过程中需要对其进行评估，以降低贝宁青光眼失明的患病率。
