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[白色念珠菌性葡萄膜视乳头炎。关于一例病例的诊断与治疗讨论]

[Candida albicans uveopapillitis. Diagnostic and therapeutic discussion apropos of a case].

作者信息

Despres E, Weber M, Jouart D, Sahel J, Flament J

机构信息

Clinique Ophthalmologique, Hôpial Civil, Strasbourg.

出版信息

Bull Soc Ophtalmol Fr. 1990 Jan;90(1):105-8.

PMID:2190707
Abstract

Due to the difficulties encountered in the etiologie diagnosis of papillo uveitis along with the increasing occurrence of fungal infections (in paralleled with the number of AIDS affected patients), we found of interest to report a case of exsudative macular chorioretinitis with poor evolution under steroid therapy. In this patient infection by Candida Albicans was suspected and confirmed only after isolation and culture of the fungal from a vitrectomy specimen. A therapeutic apponch using Fluconazole (Triflucan allowed a dramatic improvement of visual acuity within a few months. Thus, vitrectomy appears as a decisive step in the diagnosis of endogenous ocular candidiasis. This diagnosis is even more difficult to suspect in patient without immun deficiency more any extraocular focal infestation.

摘要

由于乳头状体葡萄膜炎的病因诊断存在困难,且真菌感染的发生率不断上升(与艾滋病患者数量增加并行),我们发现报告一例渗出性黄斑脉络膜视网膜炎病例很有意义,该病例在类固醇治疗下病情进展不佳。在该患者中,怀疑是白色念珠菌感染,仅在从玻璃体切除标本中分离和培养出真菌后才得以确诊。使用氟康唑(大扶康)的治疗方法使视力在几个月内得到了显著改善。因此,玻璃体切除术似乎是诊断内源性眼念珠菌病的决定性步骤。在没有免疫缺陷且没有任何眼外局灶性感染的患者中,这种诊断更难怀疑。

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