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手术治疗肌张力障碍。

Surgical treatment of dystonia.

机构信息

Department of Neurosurgery, Royal Hallamshire Hospital, Sheffield, UK.

出版信息

Int Rev Neurobiol. 2011;98:573-89. doi: 10.1016/B978-0-12-381328-2.00021-3.

Abstract

Dystonia is a neurological condition characterised by abnormal muscle contractions, often causing repetitive twisting movements or abnormal postures. Varying forms of surgical intervention, for dystonia unresponsive to medical therapy, have evolved over the years and have often been associated with poor outcomes and high morbidity. The advent of stereotactic neurosurgery and the success of Deep Brain Stimulation (DBS) in treating a number of movement disorders has revolutionized the surgical treatment for dystonia. This chapter reviews the literature concerning the surgical treatment dystonic conditions, from historical origins to the current use of modern functional neurosurgical techniques.

摘要

肌张力障碍是一种以肌肉异常收缩为特征的神经疾病,常导致重复性扭曲运动或异常姿势。多年来,对于药物治疗无效的肌张力障碍,已经发展出了各种不同形式的手术干预措施,但往往与不良预后和高发病率相关。立体定向神经外科的出现和深部脑刺激(DBS)在治疗多种运动障碍方面的成功,彻底改变了肌张力障碍的手术治疗方法。本章回顾了关于肌张力障碍疾病手术治疗的文献,从历史起源到现代功能神经外科技术的应用。

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