King's College London, Medical School, Division of Cancer Studies, Section of Cancer Epidemiology, SE1 9RT London, UK.
Cancer Epidemiol. 2012 Feb;36(1):e7-12. doi: 10.1016/j.canep.2011.08.001. Epub 2011 Sep 9.
The objective of the study was to compare patterns of survival 2001-2004 in prostate cancer patients from England, Norway and Sweden in relation to age and period of follow-up.
Excess mortality in men with prostate cancer was estimated using nation-wide cancer register data using a period approach for relative survival. 179,112 men in England, 23,192 in Norway and 59,697 in Sweden were included.
In all age groups, England had the lowest survival, particularly so among men aged 80+. Overall age-standardised five-year survival was 76.4%, 80.3% and 83.0% for England, Norway and Sweden, respectively. The majority of the excess deaths in England were confined to the first year of follow-up.
The results indicate that a small but important group of older patients present at a late stage and succumb early to their cancers, possibly in combination with severe comorbidity, and this situation is more common in England than in Norway or Sweden.
本研究旨在比较 2001-2004 年英国、挪威和瑞典前列腺癌患者的生存模式，分析其与年龄和随访时间的关系。
本研究使用全国癌症登记数据，采用时期法对前列腺癌患者的超额死亡率进行估计，以相对生存率作为评估指标。该研究共纳入了来自英国的 179112 名男性、挪威的 23192 名男性和瑞典的 59697 名男性。
在所有年龄组中，英国的生存率最低，80 岁以上男性的生存率尤其低。英国、挪威和瑞典的年龄标准化五年生存率分别为 76.4%、80.3%和 83.0%。英国大部分超额死亡发生在随访的第一年。
这些结果表明，一小部分年龄较大的患者在晚期被诊断出来，且很快死于癌症，这可能与严重的合并症有关，这种情况在英国比在挪威或瑞典更为常见。
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