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腹腔镜抗反流手术后,术后吞咽困难并不能预测长期失败。

Postoperative dysphagia is not predictive of long-term failure after laparoscopic antireflux surgery.

机构信息

Division of Gastrointestinal and Minimally Invasive Surgery, The Oregon Clinic, 1040 NW 22nd Ave, Suite 560, Portland, OR 97210, USA.

出版信息

Surg Endosc. 2012 Feb;26(2):451-7. doi: 10.1007/s00464-011-1898-4. Epub 2011 Sep 10.


DOI:10.1007/s00464-011-1898-4
PMID:21909851
Abstract

INTRODUCTION: Dysphagia is a common postoperative symptom after laparoscopic antireflux surgery, usually attributed to postoperative edema or a "too tight" fundoplication. Although it is usually self-limited, it occasionally requires endoscopic dilation and rarely revisionary surgery. It has not been previously described whether postoperative dysphagia is associated with poorer long-term reflux control after fundoplication. METHODS: We hypothesized that the presence of dysphagia in the early postoperative period is associated with long-term failure of the antireflux procedure and recurrence of gastroesophageal reflux disease (GERD) symptoms. A retrospective review of a prospectively maintained database of patients undergoing antireflux surgery was performed. The study population included patients, who underwent primary laparoscopic Nissen fundoplication between the years 1991 and 2010. The presence of dysphagia on their first postoperative visit (<30 days) was used to classify them in the early-dysphagia (ED) and the no-early-dysphagia (NED) groups. The recurrence of heartburn or regurgitation, as well as the pH studies on long-term follow-up (more than 6 months) were compared between the two groups. A grading system (range 0-4) was used to measure the severity of foregut symptoms. RESULTS: 1223 patients underwent primary laparoscopic Nissen fundoplications during the study period and met the inclusion criteria. Both short and long-term follow-up was available in 821 patients, who were analyzed. 423 patients were included in the ED group, whereas 398 in the NED group. The mean regurgitation score of the ED group on the long-term follow-up was 0.25 compared to 0.20 for the NED group (P = 0.21). The heartburn score was 0.38 for the ED group compared to 0.33 for the NED group (P = 0.38). Long-term dysphagia was higher in the ED group. These findings were confirmed when ED patients were subclassified based on the degree of early post-operative dysphagia. Of the 821 patients, 599 underwent routine postoperative pH testing. The mean DeMeester score in the ED group (n = 308) was 11.7 compared to 13.2 for the NED group (n = 291; P = 0.54). The percentage of patients with abnormal pH testing was similar between the two groups. CONCLUSIONS: Early postoperative dysphagia is not associated with worse long-term GERD symptom control after primary laparoscopic antireflux surgery.

摘要

简介:腹腔镜抗反流手术后吞咽困难是一种常见的术后症状,通常归因于术后水肿或“过紧”的胃底折叠术。尽管它通常是自限性的,但偶尔需要内镜扩张,很少需要修正手术。目前还没有描述术后吞咽困难是否与胃食管反流病(GERD)症状复发后抗反流手术长期失败有关。

方法:我们假设术后早期出现吞咽困难与抗反流手术长期失败和 GERD 症状复发有关。对 1991 年至 2010 年接受抗反流手术的患者前瞻性数据库进行回顾性分析。研究人群包括接受原发性腹腔镜 Nissen 胃底折叠术的患者。将术后 30 天内(<30 天)出现吞咽困难的患者分为早期吞咽困难(ED)组和无早期吞咽困难(NED)组。比较两组长期随访(>6 个月)时烧心或反流的复发以及 pH 研究。使用分级系统(范围 0-4)来测量上消化道症状的严重程度。

结果:研究期间共有 1223 例患者接受了原发性腹腔镜 Nissen 胃底折叠术,并符合纳入标准。821 例患者有短期和长期随访资料,其中 423 例患者被纳入 ED 组,398 例患者被纳入 NED 组。ED 组在长期随访时的反流评分平均值为 0.25,而 NED 组为 0.20(P=0.21)。ED 组的烧心评分(0.38)与 NED 组(0.33)相似(P=0.38)。ED 组的长期吞咽困难发生率更高。当根据术后早期吞咽困难的严重程度对 ED 患者进行分类时,这些发现得到了证实。在 821 例患者中,599 例行常规术后 pH 检测。ED 组(n=308)的平均 DeMeester 评分(n=308)为 11.7,而 NED 组(n=291)为 13.2(P=0.54)。两组 pH 检测异常的患者百分比相似。

结论:原发性腹腔镜抗反流手术后早期出现吞咽困难与长期 GERD 症状控制不佳无关。

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本文引用的文献

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