急性抗体介导的肾移植排斥反应伴细胞性新月体形成：首例病例报告
Acute antibody-mediated rejection of renal transplant associated with cellular crescents: first case report.
作者信息
Modelli de Andrade L Gustavo, Viero R M, Carvalho M F C
机构信息
Department of Internal Medicine, Botucatu Medical School, Botucatu, Brazil.
出版信息
Transplant Proc. 2011 Sep;43(7):2798-9. doi: 10.1016/j.transproceed.2011.04.023.
Acute antibody-mediated rejection is characterized by histological abnormalities such as glomerulitis, capillaritis, or thrombosis associated with presence of C4d and specific anti-donor antibodies. Reports on the association of glomerular injuries with cellular crescents in antibody-mediated rejection are not found in the literature. We report a unique case of antibody-mediated rejection associated with cellular crescents and suggest that such histological abnormality should be considered in the differential diagnosis of acute antibody-mediated rejection.
急性抗体介导的排斥反应的特征是组织学异常，如肾小球炎、毛细血管炎或血栓形成，并伴有C4d和特异性抗供体抗体的存在。文献中未发现关于抗体介导的排斥反应中肾小球损伤与细胞性新月体相关性的报道。我们报告了一例与细胞性新月体相关的抗体介导的排斥反应的独特病例，并建议在急性抗体介导的排斥反应的鉴别诊断中应考虑这种组织学异常。
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