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[心脏再同步治疗:新数据与技术进展]

[Cardiac resynchronisation therapy : new data and technical developments].

作者信息

Butter C

机构信息

Abt. Kardiologie, Herzzentrum Brandenburg in Bernau, Deutschland.

出版信息

Herz. 2011 Oct;36(7):577-85. doi: 10.1007/s00059-011-3506-8.

DOI:10.1007/s00059-011-3506-8
PMID:21912913
Abstract

Cardiac resynchronisation therapy (CRT) has opened up new perspectives over the past 10 years for highly symptomatic patients with severe systolic heart failure. The present article analyses and comments on recent publications which have lead to an expansion of the indication to patients with mild symptoms of heart failure, and which resulted in the modification of current European guidelines in 2010. The data available from narrow QRS complex studies are critically examined. Furthermore, the latest technical innovations in the field of CRT, which have helped to ease the implantation procedure and achieve higher success rates, are presented. Finally, new wireless ultrasound technology to stimulate the left ventricle, currently in an early clinical phase of evaluation, is presented as a potential alternative in the future.

摘要

在过去十年中,心脏再同步治疗(CRT)为重度收缩性心力衰竭的高度症状性患者开辟了新的前景。本文分析并评论了近期的出版物,这些出版物导致心力衰竭轻度症状患者的适应症扩大,并促成了2010年欧洲现行指南的修订。对窄QRS波群研究中可得的数据进行了批判性审查。此外,还介绍了CRT领域的最新技术创新,这些创新有助于简化植入程序并提高成功率。最后,目前处于早期临床评估阶段的用于刺激左心室的新型无线超声技术作为未来一种潜在的替代方案被提出。

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1
[Cardiac resynchronisation therapy : new data and technical developments].[心脏再同步治疗:新数据与技术进展]
Herz. 2011 Oct;36(7):577-85. doi: 10.1007/s00059-011-3506-8.
2
Sex Differences in Long-Term Outcomes With Cardiac Resynchronization Therapy in Mild Heart Failure Patients With Left Bundle Branch Block.左束支传导阻滞的轻度心力衰竭患者接受心脏再同步治疗的长期预后的性别差异
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Ventricular Electrical Delay Measured From Body Surface ECGs Is Associated With Cardiac Resynchronization Therapy Response in Left Bundle Branch Block Patients From the MADIT-CRT Trial (Multicenter Automatic Defibrillator Implantation-Cardiac Resynchronization Therapy).从体表心电图测量的心室电延迟与 MADIT-CRT 试验(多中心自动除颤器植入-心脏再同步治疗)中左束支传导阻滞患者的心脏再同步治疗反应相关。
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Echocardiography versus intracardiac electrocardiography-based optimization for cardiac resynchronization therapy : a comparative clinical long-term trial.基于超声心动图与心内心电图的心脏再同步治疗优化比较:一项长期临床对比试验
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Int J Cardiol. 2016 Jan 1;202:349-55. doi: 10.1016/j.ijcard.2015.09.023. Epub 2015 Sep 21.
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QRS axis and the benefit of cardiac resynchronization therapy in patients with mildly symptomatic heart failure enrolled in MADIT-CRT.QRS 轴与心脏再同步治疗对轻度症状心力衰竭患者的获益:MADIT-CRT 研究
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Image Integration to Guide Wireless Endocardial LV Electrode Implantation for CRT.用于心脏再同步治疗的图像整合以指导无线心内膜左心室电极植入
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本文引用的文献

1
Cardiac-resynchronization therapy for mild-to-moderate heart failure.心脏再同步治疗轻中度心力衰竭。
N Engl J Med. 2010 Dec 16;363(25):2385-95. doi: 10.1056/NEJMoa1009540. Epub 2010 Nov 14.
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Left ventricular pacing with a new quadripolar transvenous lead for CRT: early results of a prospective comparison with conventional implant outcomes.新型四极经静脉心脏再同步治疗左心室起搏导线:与传统植入术结果前瞻性比较的早期结果。
Heart Rhythm. 2011 Jan;8(1):31-7. doi: 10.1016/j.hrthm.2010.09.076. Epub 2010 Sep 29.
3
2010 Focused Update of ESC Guidelines on device therapy in heart failure: an update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC guidelines for cardiac and resynchronization therapy. Developed with the special contribution of the Heart Failure Association and the European Heart Rhythm Association.
2010年欧洲心脏病学会心力衰竭器械治疗指南重点更新:2008年欧洲心脏病学会急慢性心力衰竭诊断和治疗指南及2007年欧洲心脏病学会心脏再同步化治疗指南的更新。由心力衰竭协会和欧洲心律协会特别贡献制定。
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4
Agreement is poor among current criteria used to define response to cardiac resynchronization therapy.目前用于定义心脏再同步治疗反应的标准之间一致性较差。
Circulation. 2010 May 11;121(18):1985-91. doi: 10.1161/CIRCULATIONAHA.109.910778. Epub 2010 Apr 26.
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Evaluation of early complications related to De Novo cardioverter defibrillator implantation insights from the Ontario ICD database.评估新植入心脏除颤器与早期并发症的关系:安大略省 ICD 数据库的见解。
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6
Prevention of disease progression by cardiac resynchronization therapy in patients with asymptomatic or mildly symptomatic left ventricular dysfunction: insights from the European cohort of the REVERSE (Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction) trial.心脏再同步治疗对无症状或轻度症状性左心室功能不全患者疾病进展的预防作用:来自欧洲队列的REVERSE(收缩期左心室功能不全再同步逆转重塑)试验的见解
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7
Cardiac-resynchronization therapy for the prevention of heart-failure events.心脏再同步治疗预防心力衰竭事件
N Engl J Med. 2009 Oct 1;361(14):1329-38. doi: 10.1056/NEJMoa0906431. Epub 2009 Sep 1.
8
Characteristics of heart failure patients associated with good and poor response to cardiac resynchronization therapy: a PROSPECT (Predictors of Response to CRT) sub-analysis.与心脏再同步治疗反应良好和反应不佳相关的心力衰竭患者特征:PROSPECT(CRT 反应预测因素)子分析。
Eur Heart J. 2009 Oct;30(20):2470-7. doi: 10.1093/eurheartj/ehp368. Epub 2009 Aug 30.
9
Temporary leadless pacing in heart failure patients with ultrasound-mediated stimulation energy and effects on the acoustic window.心力衰竭患者中超声介导刺激能量的临时无导线起搏及其对声学窗口的影响
Heart Rhythm. 2009 Jun;6(6):742-8. doi: 10.1016/j.hrthm.2009.02.025. Epub 2009 Feb 24.
10
Cardiac resynchronization therapy in patients with a narrow QRS.窄QRS波患者的心脏再同步治疗
Curr Heart Fail Rep. 2009 Mar;6(1):49-56. doi: 10.1007/s11897-009-0009-5.