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[通过个体化选择药物治疗慢性肝炎来减轻内源性中毒综合征]

[Minimization of endogenous intoxication syndrome by individual choice of drugs for therapy of chronic hepatitis].

作者信息

Vasil'eva D K, Goriacheva L G, Kotiv M Ia, Alekseeva L A, Romantsov M G, Bessonova T V

出版信息

Antibiot Khimioter. 2011;56(3-4):46-50.

PMID:21913409
Abstract

The results of clinical and laboratory examination of 107 children suffering from chronic hepatitis B or C were analysed. The biochemical criteria of the endogenous intoxication were investigated. Specific blood tests with antiviral drugs were conducted before the treatment and individual therapy schemes were assigned according to the tests' results. The early and sustained virological response rates during the individual antiviral treatment of the children with chronic hepatitis C proved to be 70.83 and 62.5% respectively.

摘要

分析了107例慢性乙型或丙型肝炎患儿的临床和实验室检查结果。研究了内源性中毒的生化标准。治疗前进行了抗病毒药物的特异性血液检测,并根据检测结果制定了个体化治疗方案。慢性丙型肝炎患儿个体化抗病毒治疗期间的早期和持续病毒学应答率分别为70.83%和62.5%。

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