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脐带血库:护士和医疗保健提供者应该知道的。

Cord blood banking: what nurses and healthcare providers should know.

机构信息

Yasmin Abdullah is a Family Nurse Practitioner, La Rabida Children's Hospital, Chicago, IL, USA.

出版信息

MCN Am J Matern Child Nurs. 2011 Nov-Dec;36(6):344-50; quiz 351-2. doi: 10.1097/NMC.0b013e31822db253.

DOI:10.1097/NMC.0b013e31822db253
PMID:21918487
Abstract

Although the use of embryonic stem cells to treat disease has caused much controversy, one type of stem cell treatment has slowly and steadily shown promise but has not engendered negative ethical media attention: the use of umbilical stem cells. Umbilical cord blood (UCB) contains stem cells that have already successfully treated a variety of diseases, including leukemias, lymphomas, hemoglobinopathies, immunodeficiencies, and disorders of metabolism; ongoing research continues to explore additional diseases for potential treatment. Cord blood can be stored in private banks or public banks. Private cord blood banks save cord blood for use by the family only, at a cost. Public cord blood banks accept donations and the cord blood is then used for the general public and/or research. A review of the literature finds that public banking is the preferred recommendation over private unless there is a known family member with a disease that can currently be treated with cord blood. This article discusses cord blood banking options as well as the ethical issues and barriers facing both healthcare providers and patients when dealing with cord blood banking.

摘要

虽然胚胎干细胞在疾病治疗中的应用引起了很多争议,但是一种干细胞治疗方法已经缓慢而稳定地显示出了希望,而且没有引起负面的伦理媒体关注:使用脐带干细胞。脐带血(UCB)中含有已经成功治疗多种疾病的干细胞,包括白血病、淋巴瘤、血红蛋白病、免疫缺陷和代谢紊乱;正在进行的研究继续探索潜在的治疗方法。脐带血可以存储在私人银行或公共银行中。私人脐带血库只为家庭使用脐带血保存,这需要付费。公共脐带血库接受捐赠,然后将脐带血用于公众和/或研究。对文献的回顾发现,除非有已知的家庭成员患有目前可以用脐带血治疗的疾病,否则公共库是首选,而不是私人库。本文讨论了脐带血库的选择,以及医疗保健提供者和患者在处理脐带血库时面临的伦理问题和障碍。

相似文献

1
Cord blood banking: what nurses and healthcare providers should know.脐带血库:护士和医疗保健提供者应该知道的。
MCN Am J Matern Child Nurs. 2011 Nov-Dec;36(6):344-50; quiz 351-2. doi: 10.1097/NMC.0b013e31822db253.
2
Controversies in hybrid banking: attitudes of Swiss public umbilical cord blood donors toward private and public banking.混合银行的争议:瑞士公共脐带血捐赠者对私人和公共银行的态度。
Arch Gynecol Obstet. 2011 Jul;284(1):99-104. doi: 10.1007/s00404-010-1607-x. Epub 2010 Jul 24.
3
Concise review: Cord blood banking, transplantation and induced pluripotent stem cell: success and opportunities.简明回顾:脐带血库、移植和诱导多能干细胞:成功与机遇。
Stem Cells. 2012 Jan;30(1):55-60. doi: 10.1002/stem.770.
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Umbilical cord blood banking: beyond the public-private divide.脐带血库:超越公私之分
J Law Med. 2012 Mar;19(3):512-6.
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Umbilical cord blood banks. Ethical aspects. Public versus private banks.脐带血库。伦理问题。公共库与私人库。
Cuad Bioet. 2012 May-Aug;23(78):269-85.
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Banking on cord blood stem cells.依靠脐带血干细胞。
Nat Rev Cancer. 2008 Jul;8(7):555-63. doi: 10.1038/nrc2418. Epub 2008 Jun 12.
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[Umbilical cord blood banking: public banks or private storage?].[脐带血储存:公共库还是私人储存?]
Dtsch Med Wochenschr. 2012 Jun;137(25-26):p21. doi: 10.1055/s-0032-1301821. Epub 2012 Jun 20.
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Development of stem cells from umbilical cord blood and blood banking: "non-controversial" and "free of political and ethical debate"?脐带血干细胞的研发与血库:“毫无争议”且“不存在政治和伦理争论”?
J Law Med. 2012 Mar;19(3):490-6.
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Umbilical cord blood donation: public or private?脐带血捐献:公共还是私人的?
Bone Marrow Transplant. 2015 Oct;50(10):1271-8. doi: 10.1038/bmt.2015.124. Epub 2015 Jun 1.
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ACOG committee opinion number 399, February 2008: umbilical cord blood banking.美国妇产科医师学会委员会意见第399号,2008年2月:脐带血储存
Obstet Gynecol. 2008 Feb;111(2 Pt 1):475-7. doi: 10.1097/AOG.0b013e318166603c.

引用本文的文献

1
Hybrid umbilical cord blood banking: literature review.混合脐血库:文献综述。
Arch Gynecol Obstet. 2024 Jan;309(1):93-104. doi: 10.1007/s00404-023-07003-x. Epub 2023 Apr 24.
2
Identifying Barriers to Umbilical Cord Blood Banking in Jordan: A Cross-Sectional Survey of Obstetricians.识别约旦脐带血库的障碍:产科医生的横断面调查
Int J Hematol Oncol Stem Cell Res. 2020 Oct 1;14(4):213-225. doi: 10.18502/ijhoscr.v14i4.4474.
3
Health care professionals' knowledge, attitudes and practices relating to umbilical cord blood banking and donation: an integrative review.
医疗保健专业人员关于脐带血库存储与捐赠的知识、态度及实践:一项综合综述
BMC Pregnancy Childbirth. 2016 Apr 19;16:81. doi: 10.1186/s12884-016-0863-6.
4
Health Professionals' knowledge and attitude towards the Umbilical Cord Blood donation in Greece.希腊卫生专业人员对脐带血捐献的知识和态度。
Hippokratia. 2014 Apr;18(2):110-5.