关于灰翅夜蛾唾液腺细胞对离子电泳施加多巴胺的电反应的时间进程。
On the time course of the electrical response of salivary gland cells of Nauphoeta cinerea to ionophoretically applied dopamine.
作者信息
Blackman J G, Ginsborg B L, House C R
出版信息
J Physiol. 1979 Feb;287:81-92. doi: 10.1113/jphysiol.1979.sp012647.
Abstract
- An attempt has been made to account for the latency and slow time course of the electrical responses of salivary gland cells of Nauphoeta cinerea (Olivier) to nerve stimulation and ionophoretically applied dopamine from a pipette placed as close as possible to the acinar surface. 2. The effects have been investigated on the time course of the ionophoretic response of changes in the distance of the pipette from the acinar surface and of the amount of dopamine ejected. 3. The observed changes were smaller than those predicted by models in which the rate limiting step was assumed to be diffusion or slow receptor kinetics. Indirect evidence suggests that the time course of the response is determined by processes subsequent to receptor activation.
摘要
- 已尝试解释灰翅夜蛾（Olivier）唾液腺细胞对神经刺激以及从尽可能靠近腺泡表面放置的移液管中离子电泳施加多巴胺的电反应的潜伏期和缓慢的时间进程。2. 研究了移液管与腺泡表面距离的变化以及多巴胺排出量对离子电泳反应时间进程的影响。3. 观察到的变化小于假设限速步骤为扩散或缓慢受体动力学的模型所预测的变化。间接证据表明，反应的时间进程由受体激活后的过程决定。
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