Drug Ther Bull. 2011 Sep;49(9):105-8. doi: 10.1136/dtb.2011.02.0056.
Preterm birth (delivery before 37 weeks' gestation) is the commonest cause of neonatal mortality and morbidity in developed countries. Most of these births occur after spontaneous preterm labour. Intrauterine infection (often subclinical) is strongly implicated in the pathophysiology of spontaneous preterm labour. Consequently many published trials have assessed antibacterial therapy used with the aim of preventing preterm birth and associated adverse outcomes. Here we review this evidence and guidelines on antibacterial therapy in women at risk of preterm birth.
早产（妊娠37周前分娩）是发达国家新生儿死亡和发病的最常见原因。这些分娩大多发生在自发性早产之后。宫内感染（通常为亚临床感染）与自发性早产的病理生理学密切相关。因此，许多已发表的试验评估了旨在预防早产及相关不良结局的抗菌治疗。在此，我们综述关于早产风险女性抗菌治疗的这一证据和指南。
