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AIDS/HIV. Converging on an HIV vaccine.

作者信息

Korber Bette, Gnanakaran S

机构信息

Theoretical Biology and Biophysics, T6, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.

出版信息

Science. 2011 Sep 16;333(6049):1589-90. doi: 10.1126/science.1211919.

DOI:10.1126/science.1211919

PMID:21921189

Abstract

摘要

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AIDS/HIV. Converging on an HIV vaccine.

作者信息

Korber Bette, Gnanakaran S

机构信息

Theoretical Biology and Biophysics, T6, Los Alamos National Laboratory, Los Alamos, NM 87545, USA.

出版信息

Science. 2011 Sep 16;333(6049):1589-90. doi: 10.1126/science.1211919.

DOI:10.1126/science.1211919

PMID:21921189

Abstract

摘要

相似文献

AIDS/HIV. Converging on an HIV vaccine.

Science. 2011 Sep 16;333(6049):1589-90. doi: 10.1126/science.1211919.

Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.

Science. 2011 Sep 16;333(6049):1593-602. doi: 10.1126/science.1207532. Epub 2011 Aug 11.

AIDS/HIV. A boost for HIV vaccine design.

Science. 2010 Aug 13;329(5993):770-3. doi: 10.1126/science.1194693.

Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.

Science. 2011 Sep 16;333(6049):1633-7. doi: 10.1126/science.1207227. Epub 2011 Jul 14.

Increasing the potency and breadth of an HIV antibody by using structure-based rational design.

Science. 2011 Dec 2;334(6060):1289-93. doi: 10.1126/science.1213782. Epub 2011 Oct 27.

Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.

Science. 2011 Oct 21;334(6054):373-6. doi: 10.1126/science.1209368.

Isolation and characterization of a novel neutralizing antibody targeting the CD4-binding site of HIV-1 gp120.

Antiviral Res. 2016 Aug;132:252-61. doi: 10.1016/j.antiviral.2016.06.013. Epub 2016 Jul 5.

Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs.

J Mol Biol. 2006 Mar 17;357(1):82-99. doi: 10.1016/j.jmb.2005.12.062. Epub 2006 Jan 9.

Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.

Science. 2010 Aug 13;329(5993):811-7. doi: 10.1126/science.1192819. Epub 2010 Jul 8.

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.

Science. 2001 Aug 10;293(5532):1155-9. doi: 10.1126/science.1061692.

引用本文的文献

The Molecular Basis of pH-Modulated HIV gp120 Binding Revealed.

Evol Bioinform Online. 2019 Mar 7;15:1176934319831308. doi: 10.1177/1176934319831308. eCollection 2019.

Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity.

Vaccines (Basel). 2014 Mar 25;2(2):196-215. doi: 10.3390/vaccines2020196.

HIV-1 Env DNA vaccine plus protein boost delivered by EP expands B- and T-cell responses and neutralizing phenotype in vivo.

PLoS One. 2013 Dec 31;8(12):e84234. doi: 10.1371/journal.pone.0084234. eCollection 2013.

Anti-HIV double variable domain immunoglobulins binding both gp41 and gp120 for targeted delivery of immunoconjugates.

PLoS One. 2012;7(10):e46778. doi: 10.1371/journal.pone.0046778. Epub 2012 Oct 4.

Evolutionary dynamics of HIV at multiple spatial and temporal scales.

J Mol Med (Berl). 2012 May;90(5):543-61. doi: 10.1007/s00109-012-0892-1. Epub 2012 May 3.

Biochem Biophys Res Commun. 2012 Jan 27;417(4):1164-9. doi: 10.1016/j.bbrc.2011.12.089. Epub 2011 Dec 27.