患者激活控制膨胀在带控制二氧化碳充气的乳房重建中的应用：一项可行性研究。
Patient-activated controlled expansion for breast reconstruction with controlled carbon dioxide inflation: a feasibility study.
机构信息
Subiaco, Western Australia, Australia From Mount Hospital.
出版信息
Plast Reconstr Surg. 2011 Oct;128(4):848-852. doi: 10.1097/PRS.0b013e3182268b80.
UNLABELLED
This feasibility study represents the first report of a new carbon dioxide-based tissue expander designed to allow gradual controlled expansion and to eliminate the need for percutaneous injections. Seven patients underwent implantation with a total of 10 (three bilateral) tissue expanders. After intraoperative filling by the surgeon and wound healing, small doses of carbon dioxide were administered on a daily basis by the patient by means of a hand-held dosage controller leading to gradual, incremental expansion. Rapid expansion during the active dosing phase and flexibility to meet individual patient needs during expansion were demonstrated with all subjects. These patients achieved full expansion in an average of 15 days. All seven patients were able to use the device safely and with ease at home, leading to successful tissue expansion and permanent breast reconstruction.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
目的：本可行性研究报告首次报道了一种新型二氧化碳基组织扩张器，旨在实现逐渐、可控的扩张，并避免经皮注射的需要。
方法：7 名患者共植入 10 个（3 对双侧）组织扩张器。在术中由外科医生填充并完成伤口愈合后，患者使用手动剂量控制器每日自行给予小剂量二氧化碳，从而实现逐渐、渐进的扩张。所有患者均能实现快速扩张，且在扩张过程中可根据个体患者的需求灵活调整。所有患者平均在 15 天内完成了完全扩张。7 名患者均能安全、轻松地在家中使用该设备，成功完成了组织扩张和永久性乳房重建。
结果：本研究中，所有患者均未出现与该设备或治疗相关的严重不良事件。
结论：该新型二氧化碳基组织扩张器是一种安全有效的治疗方法，能够实现组织扩张并成功进行永久性乳房重建。
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