托吡酯诱发的分离性障碍。
Topiramate-induced Dissociative Disorder.
作者信息
Sarwar Sajjad R, McGinnis Ronald A
机构信息
Department of Psychiatry, University of Toledo, Toledo, Ohio, USA.
出版信息
Innov Clin Neurosci. 2011 Aug;8(8):14-6.
Topiramate is associated with various psychiatric and neurocognitive side effects. We report a case of a 21-year-old woman who was prescribed topiramate for the treatment of migraine headaches by her neurologist. She developed episodes of dissociation while receiving topiramate. These episodes increased when the dose of medicine was increased. The frequency of these episodes decreased as the medicine dose was tapered down, and these episodes eventually stopped after the medicine was discontinued. There was no recurrence of symptoms during the 23-week follow-up period.
托吡酯与多种精神和神经认知方面的副作用相关。我们报告一例21岁女性病例，其神经科医生为治疗偏头痛给她开了托吡酯。她在服用托吡酯期间出现了分离发作。当药物剂量增加时，这些发作增多。随着药物剂量逐渐减少，这些发作的频率降低，在停药后这些发作最终停止。在23周的随访期内症状未复发。
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