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前庭神经炎:是否存在非对称分布的证据?

Vestibular neuritis: is there any evidence of an asymmetric distribution?

机构信息

Department of Ear, Nose and Throat, Elblandklinikum Radebeul, Heinrich-Zille-Str. 13, 01445 Radebeul, Germany.

出版信息

Eur Arch Otorhinolaryngol. 2012 Apr;269(4):1091-4. doi: 10.1007/s00405-011-1763-z. Epub 2011 Sep 16.

Abstract

Statistics in the literature showed that neuro-otological diseases (i.e. sudden hearing loss or tinnitus) occur predominantly in the left ear. In a seven-study meta-analysis of patients suffering from vestibular neuritis, Reiß found no clear dominance of one side (50.8% on the right side, 48.4% on the left side and 0.8% on both sides). The purpose of this study is to investigate the laterality of vestibular neuritis in a distinct population of patients. Lateralization of vestibular neuritis was studied in 160 patients treated at Elblandklinikum Radebeul from January 2004 to December 2009. There was a statistically non-significant dominance of the right side in the total sample, specifically in female patients (57% right vs. 40% left), but not in male patients. The study confirms the results of the meta-analysis: that there is no relevant side dominance in patients suffering from vestibular neuritis. In addition to the caloric test, the head impulse test was performed in 157 patients. In 92% of these patients, the disturbance of vestibular function could be confirmed with the head impulse test. This test is altogether a clinically useful instrument especially for follow-up, but also for diagnosis.

摘要

文献中的统计数据表明,神经耳科学疾病(如突发性听力损失或耳鸣)主要发生在左耳。在一项对前庭神经炎患者的七项研究的荟萃分析中,Reiß 并未发现任何一侧明显占优势(右侧 50.8%,左侧 48.4%,两侧均为 0.8%)。本研究旨在调查特定患者群体中前庭神经炎的偏侧性。2004 年 1 月至 2009 年 12 月,Elblandklinikum Radebeul 对 160 例接受治疗的患者进行了前庭神经炎的偏侧性研究。在总样本中,右侧具有统计学上的非显著优势,特别是在女性患者中(57%右侧对 40%左侧),但在男性患者中则没有。该研究证实了荟萃分析的结果:即前庭神经炎患者不存在相关的侧优势。除了冷热测试外,本研究还对 157 例患者进行了头部脉冲测试。在这些患者中,92%的患者可以通过头部脉冲测试确认前庭功能障碍。该测试是一种临床有用的工具,特别是在随访时,也可用于诊断。

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