Sevcíková S, Nemec P, Pour L, Hájek R
Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Klin Onkol. 2011;24 Suppl:S34-8.
Multiple myeloma (MM) is the second most common hematological cancer. It is a very heterogeneous disease characterized by large genomic complexity, recurrent amplifications and/or deletions in the genome leading to different clinical manifestations and survival of patients. Thus, genomics plays an important role in identifying agents responsible for pathogenesis, prognosis and disease stratification of MM.
多发性骨髓瘤（MM）是第二常见的血液系统癌症。它是一种高度异质性疾病，其特征是基因组复杂性高，基因组中反复出现扩增和/或缺失，导致患者出现不同的临床表现和生存情况。因此，基因组学在确定导致MM发病机制、预后和疾病分层的因素方面发挥着重要作用。
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