Kirkness Carmen S, Yu Junhua, Asche Carl V
Pharmacotherapy Outcomes Research Center, Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA.
J Pain Palliat Care Pharmacother. 2008;22(4):336-48. doi: 10.1080/15360280802536649.
Comorbidities can affect how patients experience pain associated with chronic disease. Despite numerous studies on the association of pain with chronic conditions, few account for the multiple comorbidities associated with the highly prevalent chronic disease osteoarthritis (OA). OA generally is not lethal but it greatly impacts health care utilization and costs mainly primarily due to pain and disability. This paper describes how comorbidities impact OA pain reporting. We identified the common comorbidities associated with OA and examined the comorbidity measures utilized to identify the comorbidities. Using the identified comorbidities, we related how they may contribute to the pain experience for OA patients. We describe how OA treatment and multiple comorbidities may impact on treatment decisions.
合并症会影响患者体验与慢性病相关疼痛的方式。尽管有大量关于疼痛与慢性病关联的研究，但很少有研究考虑到与高度流行的慢性病骨关节炎（OA）相关的多种合并症。OA通常不会致命，但它主要因疼痛和残疾而对医疗保健的利用和成本产生重大影响。本文描述了合并症如何影响OA疼痛报告。我们确定了与OA相关的常见合并症，并研究了用于识别这些合并症的合并症测量方法。利用已确定的合并症，我们阐述了它们可能如何导致OA患者的疼痛体验。我们描述了OA治疗和多种合并症可能如何影响治疗决策。
