Liu Jun, Liu Yue, Lu Guo-Ying, Li Zhi, Li Xiao-Feng, Wang Yu-Shan, Fang Pi-Hua
Center for Cardiac Function Test, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2011 Jun;39(6):494-6.
To investigate the time course of positive head-up tilt test (HUTT) for patients with suspected vasovagal syncope.
Consecutive patients referred to the syncope unit of our center for recurrent unexplained syncope were included. The HUTT consisted of a 30 minute passive basic phase and a 20 minute sublingual nitroglycerin provocation phase if syncope did not develop during the passive phase.
Positive HUTT was observed in 427 out of 773 consecutive patients (55.2%) patients including 43 patients (10.1%) during the passive basic phase and 384 patients (89.9%) during the nitroglycerin provocation phase. During the basic phase, the positive Hutt developed at 7.5 minute (n = 2) and peaked at 22.5th minute (20.9%, n = 9) and then decreased gradually. Most positive reactions (93.0%, n = 40) occurred between the 10 and 25 minutes during the basic phase. During the nitroglycerin provocation phase, the percentage of positive reactions increased rapidly after sublingual nitroglycerin, peaked at the 10th minute (35.7%, n = 137) and decreased thereafter. Most positive reactions (96.1%, n = 369) occurred within the first 15 minutes of provocation phase.
The appropriate duration for HUTT test could be modified to a 25 minutes passive basic phase plus 15 minutes nitroglycerin provocation phase.
探讨疑似血管迷走性晕厥患者直立倾斜试验（HUTT）的阳性时间过程。
纳入因反复不明原因晕厥转诊至本中心晕厥单元的连续患者。HUTT包括30分钟的被动基础阶段，若在被动阶段未发生晕厥，则进入20分钟的舌下含服硝酸甘油激发阶段。
773例连续患者中有427例（55.2%）出现阳性HUTT，其中43例（10.1%）在被动基础阶段出现，384例（89.9%）在硝酸甘油激发阶段出现。在基础阶段，阳性Hutt在7.5分钟时出现（n = 2），在第22.5分钟达到峰值（20.9%，n = 9），然后逐渐下降。大多数阳性反应（93.0%，n = 40）发生在基础阶段的10至25分钟之间。在硝酸甘油激发阶段，舌下含服硝酸甘油后阳性反应百分比迅速增加，在第10分钟达到峰值（35.7%，n = 137），此后下降。大多数阳性反应（96.1%，n = 369）发生在激发阶段的前15分钟内。
HUTT试验的合适时长可调整为25分钟的被动基础阶段加15分钟的硝酸甘油激发阶段。
