Scherling B, Verder H, Nielsen M D, Christensen P, Giese J
Department of Pediatrics, Holbaek Hospital, Denmark.
Scand J Urol Nephrol. 1990;24(2):123-5. doi: 10.3109/00365599009180376.
A 13-year-old girl presented with lassitude, polyuria and hypokalemia. Plasma renin concentration and urinary prostaglandin excretion were elevated, whereas plasma aldosterone concentration, urinary aldosterone excretion and blood pressure were normal. A diagnosis of Bartter's syndrome was made. The result of treatment with oral potassium was unsatisfactory. Treatment with acetylsalicylic acid had some effect, but an allergic reaction rendered withdrawal necessary. Treatment with the angiotensin converting enzyme inhibitor captopril and oral potassium led to clinical and biochemical improvement.
一名13岁女孩出现倦怠、多尿和低钾血症。血浆肾素浓度和尿前列腺素排泄升高,而血浆醛固酮浓度、尿醛固酮排泄和血压正常。诊断为巴特综合征。口服钾治疗效果不佳。阿司匹林治疗有一定效果,但因过敏反应不得不停药。血管紧张素转换酶抑制剂卡托普利与口服钾联合治疗使临床症状和生化指标得到改善。