Southern Cross Business School, Southern Cross University, New South Wales, Australia.
Clin Ther. 2011 Oct;33(10):1466-74. doi: 10.1016/j.clinthera.2011.08.009. Epub 2011 Sep 15.
This study investigated the association between body mass index (BMI) and changes in BMI over time with health-related quality-of-life data among a general and representative sample of the Australian population.
The sample consisted of respondents between the ages of 18 and 79 who completed the Household, Income and Labour Dynamics in Australia (HILDA) Survey in 2007 and 2009. These respondents completed the SF-36 questionnaire and provided data on their height, weight, medical conditions, and sociodemographic characteristics. SF-36 questionnaire responses were converted into health state utility values using the SF-6D algorithm. Regression analysis was used to examine the relationship between BMI and utility, controlling for a range of obesity-related medical conditions and sociodemographic characteristics.
Obese men (BMI value≥30) had, on average, a lower utility score (-0.0190, P < 0.001) than men within an "acceptable" BMI range (BMI 18.5 to <25). Obese women (BMI value ≥30) also had, on average, a lower utility score (-0.0338, P < 0.001) than women within an acceptable BMI range (18.5 to<25). Although BMI was not associated longitudinally with utility, there was a statistically significant negative longitudinal relationship between arthritis (-0.0153, P < 0.01) and depression/anxiety disorders (-0.0358, P < 0.001) and utility.
Cross-sectional results suggest that BMI is negatively associated with utility and that further investigation of the longitudinal relationship between BMI and utility is warranted.
本研究旨在调查澳大利亚一般代表性人群的体重指数(BMI)与 BMI 随时间变化与健康相关生活质量数据之间的关系。
该样本由年龄在 18 至 79 岁之间的受访者组成,他们在 2007 年和 2009 年完成了澳大利亚家庭、收入和劳动力动态调查(HILDA)。这些受访者完成了 SF-36 问卷,并提供了他们的身高、体重、医疗状况和社会人口特征数据。SF-36 问卷的回答使用 SF-6D 算法转换为健康状态效用值。回归分析用于检查 BMI 和效用之间的关系,同时控制了一系列肥胖相关的医疗状况和社会人口特征。
肥胖男性(BMI 值≥30)的平均效用评分较低(-0.0190,P<0.001),而处于“可接受”BMI 范围内(BMI 为 18.5 至<25)的男性。肥胖女性(BMI 值≥30)的平均效用评分也较低(-0.0338,P<0.001),而处于可接受 BMI 范围内(18.5 至<25)的女性。尽管 BMI 与效用没有纵向相关,但关节炎(-0.0153,P<0.01)和抑郁/焦虑障碍(-0.0358,P<0.001)与效用之间存在统计学上显著的负向纵向关系。
横断面结果表明 BMI 与效用呈负相关,需要进一步研究 BMI 与效用之间的纵向关系。