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内窥镜胸交感神经切断术治疗多汗症和面部潮红的远期疗效。

Late results of endoscopic thoracic sympathectomy for hyperhidrosis and facial blushing.

机构信息

Department of Surgery, Borås Hospital, Borås, Sweden.

出版信息

Br J Surg. 2011 Dec;98(12):1719-24. doi: 10.1002/bjs.7682. Epub 2011 Sep 16.

Abstract

BACKGROUND

The purpose of this study was to clarify the long-term effects, side-effects and overall satisfaction rates of endoscopic thoracic sympathectomy (ETS) used in the treatment of hyperhidrosis and facial blushing.

METHODS

Some 3015 patients had bilateral ETS from 1989 to 1998. A questionnaire follow-up was used. Some of the patients had participated in a previous follow-up study, and the answers in both surveys were compared.

RESULTS

A total of 1700 patients responded (56·4 per cent); mean(s.d.) follow-up was 14·6(2·4) years. The best result was achieved for palmar hyperhidrosis (95·6 per cent) compared with axillary hyperhidrosis (68·9 per cent), facial hyperhidrosis (83 per cent) and facial blushing (72·8 per cent) (P < 0·001). Compensatory sweating, the main side-effect, was present in 80·0 per cent. Some 6·5 per cent were dissatisfied and 13·5 per cent regretted having the procedure. Patients with palmar hyperhidrosis were more satisfied (86·6 per cent) than those with axillary hyperhidrosis (66·0 per cent), facial hyperhidrosis (74 per cent) or facial blushing (73·5 per cent) (P < 0·001). Women were more satisfied than men (85·4 versus 71·4 per cent; P < 0·001). The procedure regret rate rose from 7·8 per cent in the first survey to 13·5 per cent in the present one.

CONCLUSION

ETS had an excellent and lasting effect on palmar hyperhidrosis. The effect on facial and axillary hyperhidrosis and facial blushing was less rewarding. The procedure regret rate increased over time.

摘要

背景

本研究旨在阐明内镜胸交感神经切断术(ETS)治疗多汗症和面部潮红的长期效果、副作用和总体满意度。

方法

1989 年至 1998 年间,对 3015 例患者进行了双侧 ETS。采用问卷调查进行随访。部分患者曾参加过之前的随访研究,比较了两次调查的答案。

结果

共有 1700 例患者做出回应(56.4%);平均(标准差)随访时间为 14.6(2.4)年。手掌多汗症(95.6%)的疗效最好,与腋窝多汗症(68.9%)、面部多汗症(83%)和面部潮红(72.8%)相比(P<0.001)。代偿性出汗是主要的副作用,发生率为 80.0%。约有 6.5%的患者不满意,13.5%的患者后悔接受了该手术。手掌多汗症患者的满意度(86.6%)高于腋窝多汗症(66.0%)、面部多汗症(74.0%)或面部潮红(73.5%)(P<0.001)。女性比男性更满意(85.4%比 71.4%;P<0.001)。手术后悔率从第一次调查的 7.8%上升到本次调查的 13.5%。

结论

ETS 对手掌多汗症有极好且持久的疗效。对面部和腋窝多汗症及面部潮红的疗效则不尽如人意。手术后悔率随时间推移而增加。

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