Hunninghake D B
Heart Disease Prevention Clinic, University of Minnesota, Minneapolis.
Endocrinol Metab Clin North Am. 1990 Jun;19(2):345-60.
The bile-acid sequestrants, nicotinic acid and lovastatin, are the most effective drugs for lowering LDL-cholesterol. Nicotinic acid and gemfibrozil are more effective for lowering triglycerides and increasing HDL. Important considerations for proper selection of drugs in the treatment of the various dyslipoproteinemias are presented. Currently available drugs now permit effective control of blood lipid and lipoprotein levels.
胆汁酸螯合剂、烟酸和洛伐他汀是降低低密度脂蛋白胆固醇最有效的药物。烟酸和吉非贝齐在降低甘油三酯和提高高密度脂蛋白方面更有效。文中介绍了在治疗各种血脂蛋白异常时正确选择药物的重要考虑因素。目前可用的药物现在能够有效控制血脂和脂蛋白水平。
