Arthur G James Cancer Hospital, Ohio State University Medical Center, Department of Radiation Oncology, 300 West 10th Avenue, Columbus, OH 43210, USA.
Expert Rev Anticancer Ther. 2011 Sep;11(9):1429-36. doi: 10.1586/era.11.110.
Head and neck cancer is typically managed with surgery, radiation therapy, chemotherapy or various combinations of the above. In patients who develop recurrence after radiation therapy, treatment options are limited. Reirradiation can be offered but the amount of additional radiation that can be given is limited and there is an increased risk of serious complications. Stereotactic radiation therapy has been used as a boost or salvage therapy at recurrence for nasopharyngeal carcinoma. The use of stereotactic body radiation therapy for head and neck cancer has expanded to include sites outside of the base of skull region, especially in the recurrent setting, and clinical data are emerging. This article will highlight some of the technical and clinical advances in this area.
头颈部癌症通常采用手术、放疗、化疗或上述方法的各种组合进行治疗。对于接受放疗后复发的患者，治疗选择有限。可以进行再放疗，但可给予的额外放射剂量有限，且严重并发症的风险增加。立体定向放疗已被用作鼻咽癌复发时的增敏或挽救治疗。立体定向体部放疗已扩展用于颅底区域以外的头颈部癌症部位，特别是在复发情况下，且正在出现临床数据。本文将重点介绍该领域的一些技术和临床进展。
