Sado Daniel M, Flett Andrew S, Moon James C
Department of Inherited Cardiac Disease, The Heart Hospital, 16-18 Westmoreland Street, London, W1G 8PH, UK.
Future Cardiol. 2011 Sep;7(5):643-50. doi: 10.2217/fca.11.45.
Diffuse myocardial fibrosis (DMF) is an important marker in many cardiac diseases, but its utility has been limited by the need for biopsy for its assessment. An accurate noninvasive method for DMF assessment could transform cardiology. This review explores the basic biology of DMF and then discusses the ability of various cardiac imaging modalities to evaluate this variable, speculating on how this area of research may develop over the next few years.
弥漫性心肌纤维化(DMF)是许多心脏疾病的重要标志物,但其应用因需要通过活检进行评估而受到限制。一种准确的无创性DMF评估方法可能会改变心脏病学。本文综述探讨了DMF的基础生物学,然后讨论了各种心脏成像方式评估这一变量的能力,并推测了该研究领域在未来几年可能的发展方向。