Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
PLoS One. 2011;6(9):e24295. doi: 10.1371/journal.pone.0024295. Epub 2011 Sep 8.
HIV prevalence among men who have sex with men (MSM) and transgender (TG) persons is high and increasing in Chiang Mai, northern Thailand.
To describe demographic, socioeconomic, sexual behavior and interest in future HIV prevention trials among gay and bisexual MSM and TG presenting for HIV testing (VCT) and pre-screening for the iPrEx pre-exposure chemoprophylaxis trail.
In 2008-09, MSM/TG participants attending VCT were interviewed and tested for HIV and STI. Univariate and multivariate regression analyses were done to assess associations with HIV infection.
A total of 551 MSM clients (56.1% gay, 25.4% TG, and 18.5% bisexual (BS)) were enrolled. The mean age was 23.9 years. HIV prevalence among MSM overall was 12.9% (71/551); 16.5% among gay men, 9.3% among TG, and 6.9% among BS. Consistent use of condom was low, 33.3% in insertive anal sex and 31.9% in receptive anal sex. Interest in participation was high, 86.3% for PrEP, 69.7% for HIV vaccine trials, but 29.9% for circumcision. HIV was independently associated with being gay identified, aOR 2.8, p = 0.037 and with being aged 25-29, aOR 2.7, p = 0.027. Among repeat testers, HIV incidence was 8.2/100 PY, 95% CI, 3.7/100PY to 18.3/100PY.
HIV risks and rates varied by self-reported sexual orientation and gender identity. HIV was associated with sexual practices, age, and being gay-identified. These are populations are in need of novel prevention strategies and willing to participate in prevention research.
在泰国北部清迈，男男性行为者（MSM）和跨性别者（TG）中的艾滋病毒感染率很高且呈上升趋势。
描述男同性恋者和双性恋者以及前来接受艾滋病毒检测（VCT）和 iPrEx 暴露前预防试验预筛查的跨性别者的人口统计学、社会经济、性行为特征和对未来艾滋病毒预防试验的兴趣。
在 2008-09 年，参加 VCT 的男同性恋者和跨性别者接受了访谈和艾滋病毒及性传播感染检测。进行单变量和多变量回归分析，以评估与艾滋病毒感染的相关性。
共纳入 551 名男同性恋者客户（56.1%为男同性恋，25.4%为跨性别者，18.5%为双性恋者（BS））。平均年龄为 23.9 岁。男同性恋者和双性恋者的总体艾滋病毒感染率为 12.9%（71/551）；男同性恋者为 16.5%，跨性别者为 9.3%，双性恋者为 6.9%。在插入性肛交和接受性肛交中，始终使用安全套的比例较低，分别为 33.3%和 31.9%。对参与的兴趣很高，86.3%对 PrEP 有兴趣，69.7%对艾滋病毒疫苗试验有兴趣，但 29.9%对包皮环切术有兴趣。HIV 与同性恋身份识别独立相关，优势比（aOR）为 2.8，p=0.037，与 25-29 岁年龄独立相关，aOR 为 2.7，p=0.027。在重复检测者中，HIV 发病率为 8.2/100 人年，95%置信区间为 3.7/100 人年至 18.3/100 人年。
HIV 风险和发生率因自我报告的性取向和性别认同而异。HIV 与性行为、年龄和同性恋身份识别有关。这些人群需要新的预防策略，并愿意参与预防研究。
